1-甲基-4-(1-甲基乙烯基)苯合成路线 （共 150 条）
反应条件
diethyl ether; tris(pentafluorophenyl)-borane; hydrogen in dichloromethane-d2
T=20°C; P=60804.1 Torr; 24 h; Catalytic behavior;
参考文献
Hounjet, Lindsay J.; Bannwarth, Christoph; Garon, Christian N.; Caputo, Christopher B.; Grimme, Stefan; Stephan, Douglas W.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 29 p. 7492 - 7495
Angew. Chem., 2013 , vol. 125, # 29 p. 7640 - 7643,4
参考文献
Ipatieff; Pines; Olberg
Journal of the American Chemical Society, 1948 , vol. 70, p. 2123,2127
参考文献
Hukki
Acta Chemica Scandinavica (1947-1973), 1949 , vol. 3, p. 279,294
反应条件
1: (i) HCl, (ii) /BRN= 635760/, AlCl3, MeNO2
2: O2, Cu(OAc)2
View Scheme
参考文献
Holtz,H.D.
Journal of Organic Chemistry, 1972 , vol. 37, # 13 p. 2069 - 2074
反应条件
in acetonitrile
144 h; Ambient temperatureanalogous reactions with other p-substituted styrenes; Product distributionMechanism;
参考文献
Fukunaga, Tadamichi; Begland, Robert W.
Journal of Organic Chemistry, 1984 , vol. 49, p. 813 - 821
反应条件
sulfuric acid; acetic acid
T=20 - 25°C; Einleiten von Isobutylen;
参考文献
Polak's Frutal Works
Patent: US2851501 , 1955 ;
反应条件
in diethyl ether
T=0°C; 6 h;
参考文献
Gadras, A.; Dunogues, J.; Calas, R.; Deleris, G.
Journal of Organic Chemistry, 1984 , vol. 49, # 3 p. 442 - 444
反应条件
1: m-chloroperbenzoic acid, disodium hydrogen phosphate / CH2Cl2 / 0.67 h / 0 - 8 °C
2: 2percent sulfuric acid / diethyl ether / 0.33 h / 2 - 4 °C
View Scheme
参考文献
Matsumoto; Takeda; Iwata; Sakamoto; Ishida
Chemical and Pharmaceutical Bulletin, 1994 , vol. 42, # 6 p. 1191 - 1197
反应条件
1: With sodium tetrahydroborate; boron trifluoride diethyl etherate in tetrahydrofuran
T=0 - 20°C; Addition; 2.5 h;
2: With anhydrous potassium sulfate; potassium hydrogensulfate; oxone in water
T=0 - 20°C; Oxidation;
参考文献
Pfizer Products Inc.
Patent: EP1167329 A2, 2002 ;
Location in patent: Page 8 ;
反应条件
1: 1-methyl-4-(methylethenyl)benzene With ammonium chloride
T=80°C; 7 h;
2: formaldehyd With hydrogenchloride; manganese(IV) oxide
T=80°C; 7 h;
参考文献
Soldatenkov; Polyanskii; Temesgen; Soldatova; Sergeeva; Kolyadina; Lobanov
Mendeleev Communications, 2001 , vol. 11, # 4 p. 154 - 155
