2,2,6,6-四甲基环己酮合成路线 （共 45 条）
反应条件
in cyclohexane
25.5 h; Irradiation;
参考文献
Starr,J.E.; Eastman,R.H.
Journal of Organic Chemistry, 1966 , vol. 31, p. 1393 - 1402
反应条件
1: 73 percent / NH2OH*HCl; NaOAc / methanol / 72 h / Heating
2: 88 percent / t-BuOCl / CH2Cl2; 2-methyl-propan-2-ol / 1.5 h / 0 °C
View Scheme
参考文献
Filip, Sorin V.; Sewald, Norbert
Synthesis, 2005 , # 20 art. no. T06205SS, p. 3565 - 3570
反应条件
1: 57 percent / hydroxylamine hydrochloride, 15percent aq. NaOH / aq. ethanol / 120 h / Heating
2: 39 percent / nitrosyl chloride / tetrahydrofuran; pyridine / 2.5 h / -20 °C
3: 90 percent / ammonia / tetrahydrofuran / 4 h / 0 °C
View Scheme
参考文献
Guziec, Frank S.; Russo, Joseph M.
Synthesis, 1984 , # 6 p. 479 - 481
反应条件
1: H2S gas, HCl gas, trimethyl orthoformate / ethanol
2: 12 percent / 50 percent aq. NaOH, benzyl(triethyl)ammonium chloride / 1.25 h / Ambient temperature; vigorous stirring
View Scheme
参考文献
Mloston, Grzegorz; Romanski, Jaroslaw; Swiatek, Anna; Heimgartner, Heinz
Helvetica Chimica Acta, 1999 , vol. 82, # 6 p. 946 - 956
反应条件
hydrogenchloride; hydrogen sulfide; trimethyl orthoformate in methanol
T=0°C;
参考文献
Huisgen, Rolf; Fisera, Lubor; Giera, Henry; Sustmann, Reiner
Journal of the American Chemical Society, 1995 , vol. 117, # 38 p. 9671 - 9678
