sodium carbonate; bis-triphenylphosphine-palladium(II) chloride in 1,4-dioxane T=150°C; Suzuki coupling; 0.333333 h; microwave irradiation;

1: 90 percent / Et3N / CH2Cl2 / 0.33 h / -78 - 20 °C 2: 92 percent / sodium carbonate / PdCl2(PPh3)2 / dioxane / 0.33 h / 150 °C / microwave irradiation View Scheme

hydrogen bromide; pyridinium hydrobromide perbromide 1.) acetic acid, RT, 1 h, 2.) 150 deg C, 2 h; Yield given. Multistep reaction;