(S)-(+)-2-(三氟甲基)吡咯烷合成路线 (共 2 条)
反应条件
1: With dimethylsulfide borane complex in tetrahydrofuran Inert atmosphereReflux; 2: With hydrogenchloride in tetrahydrofuran; methanol T=-20°C; 1 h; 3: With sodium hydroxide in tetrahydrofuran; methanol; water
参考文献
Bezdudny, Andrii V.; Alekseenko, Anatoliy N.; Mykhailiuk, Pavel K.; Manoilenko, Olga V.; Shishkin, Oleg V.; Pustovit, Yurii M.
European Journal of Organic Chemistry, 2011 , # 9 p. 1782 - 1785
反应条件
sulfur(IV) fluoride; hydrogen fluoride T=120°C; 8 h;
参考文献
Shustov, G. V.; Denisenko, S. N.; Chervin I. I.; Kostyanovskii, R. G.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1988 , vol. 37, p. 1422 - 1427
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1988 , # 7 p. 1606 - 1612