反式-3-甲氧羰基-2,2,5,5-四甲基-4-硝基甲基-吡咯烷-1-氧基合成路线 （共 2 条）
反应条件
1,5-diazabicyclo[5.4.0]-undec-7-ene in acetonitrile T=50°C; 8 h;
参考文献
Hideg, Kalman; Hankovszky, H. Olga; Halasz, H. Anna; Sohar, Pal
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2905 - 2912
反应条件
1: 1.) KOH, 2.) KMnO4, MgSO4 / 1.) MeOH, 0 deg C, 15 min, 2.) MeOH, H2O, 0 deg C, 2 h 2: 80 percent / NaBH4 / ethanol / 0.5 h / Ambient temperature 3: Et3N / CH2Cl2 / 1 h / Ambient temperature 4: NaI / tetrahydrofuran / 48 h / Heating 5: 82 percent / NaOH, H2O / ethanol / 0.5 h / 78 °C 6: 1.) HCl, 2.) Br2 / 1.) EtOH, 78 deg C, 30 min, 2.) CHCl3, 61 deg C, 30 min View Scheme
参考文献
Kalai, Tamas; Balog, Maria; Jekoe, Jozsef; Hideg, Kalman
Synthesis, 1999 , # 6 p. 973 - 980
