1: 96 percent / H2 / 10percent Pd/C / methanol / 12 h 2: 1.) N-methylmorpholine, isobutyl chloroformate / 1.) CH2Cl2, -10 deg C, 3 min, 2a.) -10 deg, 15 min, 2b.) RT, 2 h 3: 100 percent / H2 / 10percent Pd/C / methanol / 1 h 4: 1-hydroxybenzotriazole, N-methylmorpholine, 1-ethyl-3-<(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 1.) -23 deg C, 2 h, 2.) RT, 16 h View Scheme