3,4-二氢异喹啉-1(2H)-酮合成路线 （共 71 条）
反应条件
1: With triphenylphosphine in tetrahydrofuran T=20°C; 1 h; 2: With water in tetrahydrofuran 24 h; Reflux;
参考文献
Heo, In-Jung; Lee, Su-Jeong; Cho, Chang-Woo
Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 1 p. 333 - 336
反应条件
1: With hydrogenchloride; sodium azide in water T=0°C; Schmidt reaction; 0.5 h; 2: With potassium carbonate in water pH=9; Cooling with ice;
参考文献
ChemMedChem, , vol. 5, # 8 p. 1300 - 1317
反应条件
zirconium dichloride in dichloromethane T=10 - 20°C; Beckmann rearrangement; 1 h;
参考文献
Torisawa, Yasuhiro; Nishi, Takao; Minamikawa, Jun-Ichi
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 10 p. 2205 - 2209
反应条件
hydrogen; acetic acid; platinum(IV) oxide P=2250.18 - 3750.3 Torr;
参考文献
Peukert, Stefan; Schwahn, Uwe; Guessregen, Stefan; Schreuder, Herman; Hofmeister, Armin
Synthesis, 2005 , # 9 art. no. C05404SS, p. 1550 - 1554
反应条件
1: 96 percent / Et3N / CH2Cl2 / 0.5 h 2: polyphosphoric acid / 2 h / 140 - 160 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 37, # 16 p. 2552 - 2563
反应条件
sodium hydroxide in water; tert-butyl alcohol 24 h; Reflux;
参考文献
Synlett, , # 8 art. no. U00511ST, p. 1121 - 1124
反应条件
tri(n-propyl)amine; tetraethylammonium chloride in diethylene glycol dimethyl ether T=140°C; 2 h; Inert atmosphere;
参考文献
Ren, Wei; Yamane, Motoki
Journal of Organic Chemistry, 2010 , vol. 75, # 24 p. 8410 - 8415
反应条件
sodium hydroxide; benzyltriethylammonium hydroxide in water; benzene 24 h; Ambient temperature;
参考文献
Rozwadowska, Maria; Brozda, Danuta
Canadian Journal of Chemistry, 1980 , vol. 58, p. 1239 - 1242
反应条件
palladium diacetate; potassium carbonate; tris-(o-tolyl)phosphine in tetrahydrofuran 156 h; Reflux;
参考文献
Wei, Ren; Yamane, Motoki
Journal of Organic Chemistry, 2009 , vol. 74, # 21 p. 8332 - 8335
反应条件
1: 93 percent / H2 / 10percent Pd/C / methanol 2: 4.3 percent Chromat. / 1) NaNO2, 3 N HCl, 2) KI / 1) H2O, 0 degC, 1.5 h, 2) warm to room temp., 4 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 19 p. 3220 - 3234
