甲基 5-醛基-1H-吡咯-2-甲酸酯合成路线 （共 12 条）
反应条件
trichlorophosphate in 1,2-dichloro-ethane T=50°C; 1 h;
参考文献
Hong, Feng; Zaidi, Javid; Pang, Yuan-Ping; Cusack, Bernadette; Richelson, Elliott
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 20 p. 2997 - 3003
反应条件
trichlorophosphate Ambient temperature;
参考文献
Tetrahedron, , vol. 48, # 8 p. 1457 - 1464
反应条件
N,N-dimethyl-formamide; trichlorophosphate in dichloromethane T=0 - 20°C; 0.5 h; Heating / reflux;
参考文献
EP1568698 A1, ;
Page/Page column 45-46 ;
反应条件
1: 63 percent / NaOMe 2: 63 percent / POCl3 View Scheme
参考文献
Chemistry - A European Journal, , vol. 6, # 4 p. 709 - 718
反应条件
1: POCl2 View Scheme
参考文献
Tetrahedron Letters, , vol. 43, # 14 p. 2589 - 2592
反应条件
1: Ag2O 2: POCl2 View Scheme
参考文献
Tetrahedron Letters, , vol. 43, # 14 p. 2589 - 2592
反应条件
POCl2 Vilsmeier-Haack reaction;
参考文献
Tetrahedron Letters, , vol. 43, # 14 p. 2589 - 2592
反应条件
Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 29, # 7 p. 777 - 780
反应条件
1: 74 percent / pyridine / 0.5 h / Ambient temperature 2: 68 percent / H2 / W-4 Raney nickel / ethanol / 2 h / 3102.9 Torr / Ambient temperature 3: 1) glacial acetic acid, 2) p-toluenesulfonic acid / 1) reflux, 17 h, 2) reflux, 2h 4: 79 percent / H2 / 5percent Rh/Al2O3 / acetic acid / 4 h / 3102.9 Torr / Ambient temperature 5: toluene / 24 h / Heating 6: 1N aq. NaOH / tetrahydrofuran / 1 h View Scheme
参考文献
Turner, William W.
Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 327 - 328
反应条件
1: 75 percent / KMnO4 2: 72 percent / NaOMe / methanol / 12 h / Heating View Scheme
参考文献
Schmuck, Garsten
Chemical Communications, 1999 , # 9 p. 843 - 844
