1: sodium methylate / methanol; N,N-dimethyl-formamide / 0 - 5 °C 2: ethyl acetate / 25 - 30 °C 3: sulfuric acid; water / 5 - 10 °C View Scheme

1.1: sodium methylate / methanol; N,N-dimethyl-formamide / 0 - 5 °C 2.1: ethyl acetate / 25 - 30 °C 3.1: sulfuric acid; water / 5 - 10 °C 4.1: ethyl acetate / 25 - 30 °C 5.1: acetic acid / dichloromethane; water / 25 - 30 °C 5.2: 25 - 30 °C View Scheme

1: sodium methylate / methanol; N,N-dimethyl-formamide / 0 - 5 °C 2: ethyl acetate / 25 - 30 °C 3: sodium methylate / methanol; N,N-dimethyl-formamide / 26 h / 25 - 45 °C 4: sulfuric acid; water / 2.5 h / 0 - 10 °C / Inert atmosphere View Scheme