sodium carbonate; trichlorophosphate in acetonitrile 1.5 h; Heating;

1: 93 percent / POCl3/Na2CO3 / acetonitrile / 1.5 h / Heating 2: TsOH*2H2O / acetonitrile / Heating; Lewis acids instead TsOH*2H2O View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11342939', constants.ctx, '0')">ammonium hydroxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '506104', constants.ctx, '0')">ethyl acetate</a> <br />16&nbsp;h;&nbsp;&nbsp;Ambient temperature;&nbsp;&nbsp;Yield given;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: sodium nitrite / ethyl acetate; H₂O / Ambient temperature<br />2: conc. ammonium hydroxide / ethyl acetate / 16 h / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: sodium nitrite / ethyl acetate; H₂O / Ambient temperature<br />2: conc. ammonium hydroxide / ethyl acetate / 16 h / Ambient temperature<br /> <br /> &nbsp;