1.1: hydrogenchloride / water; ethyl acetate / 25 - 30 °C 2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 25 - 30 °C 2.2: 1 h / 0 - 5 °C 3.1: sodium methylate / methanol; N,N-dimethyl-formamide / 0 - 5 °C 4.1: ethyl acetate / 25 - 30 °C 5.1: sulfuric acid; water / 5 - 10 °C View Scheme

1.1: hydrogenchloride / water; ethyl acetate / 25 - 30 °C 2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 25 - 30 °C 2.2: 1 h / 0 - 5 °C 3.1: sodium methylate / methanol; N,N-dimethyl-formamide / 0 - 5 °C 4.1: ethyl acetate / 25 - 30 °C 5.1: sulfuric acid; water / 5 - 10 °C 6.1: ethyl acetate / 25 - 30 °C 7.1: acetic acid / dichloromethane; water / 25 - 30 °C 7.2: 25 - 30 °C View Scheme

1.1: hydrogenchloride / water; ethyl acetate / 25 - 30 °C 2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 25 - 30 °C 2.2: 1 h / 0 - 5 °C 3.1: sodium methylate / methanol; N,N-dimethyl-formamide / 0 - 5 °C 4.1: ethyl acetate / 25 - 30 °C 5.1: sodium methylate / methanol; N,N-dimethyl-formamide / 26 h / 25 - 45 °C 6.1: sulfuric acid; water / 2.5 h / 0 - 10 °C / Inert atmosphere View Scheme