sodium hydride in N,N-dimethyl-formamide 1.5 h; Ambient temperature;

1: 1.) thionyl chloride / 1.) toluene, reflux; 2.) toluene, reflux 2: 76 percent / dioxane / 1 h / Heating 3: 80 percent / 60percent sodium hydride in oil / dimethylformamide / 1.5 h / Ambient temperature View Scheme

1: 76 percent / dioxane / 1 h / Heating 2: 80 percent / 60percent sodium hydride in oil / dimethylformamide / 1.5 h / Ambient temperature View Scheme