3-甲基-苯并呋喃-2-甲醛合成路线 （共 5 条）
反应条件
manganese(IV) oxide in benzene Ambient temperature;
参考文献
Saari, Walfred S.; Wai, John S.; Fisher, Thorsten E.; Thomas, Craig M.; Hoffman, Jacob M.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 21 p. 3792 - 3802
反应条件
1: 100 percent / DBU / benzene / 2 h / Ambient temperature 2: 87 percent / DIBAL / hexane; tetrahydrofuran / 1 h / Ambient temperature 3: 65 percent / MnO2 / benzene / Ambient temperature View Scheme
参考文献
Saari, Walfred S.; Wai, John S.; Fisher, Thorsten E.; Thomas, Craig M.; Hoffman, Jacob M.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 21 p. 3792 - 3802
反应条件
1: 87 percent / DIBAL / hexane; tetrahydrofuran / 1 h / Ambient temperature 2: 65 percent / MnO2 / benzene / Ambient temperature View Scheme
参考文献
Saari, Walfred S.; Wai, John S.; Fisher, Thorsten E.; Thomas, Craig M.; Hoffman, Jacob M.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 21 p. 3792 - 3802
反应条件
1: potassium tert-butylate / tetrahydrofuran / 4 h 2: sulfuric acid / water; THF-d8 (tetrahydrofuran-d8) / 2 h / 20 °C View Scheme
参考文献
Schevenels, Florian; Tinant, Bernard; Declercq, Jean-Paul; Marko, Istvan E.
Chemistry - A European Journal, 2013 , vol. 19, # 13 p. 4335 - 4343
反应条件
1: in ethanol
T=20°C; 18 h;
2: With sodium tetrahydroborate in ethanol
T=0 - 20°C;
参考文献
VITAS PHARMA RESEARCH PRIVATE LIMITED; RANGARAJAN, Radha; KUMAR, Rajinder; PRABHAKAR, B V; CHANDRASEKHAR, P; MALLIKARJUNA, P; BANERJEE, Ankita
Patent: WO2013/42035 A1, 2013 ;
Location in patent: Page/Page column 10 ;
