4-(苯基甲基)-1-哌嗪乙酸合成路线 （共 3 条）
反应条件
sodium hydroxide in methanol T=20°C;
参考文献
Weber, Dirk; Berger, Claudia; Eickelmann, Peter; Antel, Jochen; Kessler, Horst
Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1918 - 1930
反应条件
hydrogenchloride; sodium hydroxide in tetrahydrofuran; ethanol; dichloromethane; water
参考文献
Karl Thomae
Patent: US5994356 A1, 1999 ;
反应条件
1: 92 percent / Et3N / toluene / 20 °C 2: 100 percent / aq. NaOH / methanol / 20 °C View Scheme
参考文献
Contreras; Parrot; Sippl; Rival; Wermuth
Journal of Medicinal Chemistry, 2001 , vol. 44, # 17 p. 2707 - 2718
