1: 80 percent / imidazole / dimethylformamide / 18 h / Ambient temperature 2: 90 percent / LiAlH4, TiCl3 / tetrahydrofuran / 0.5 h / Ambient temperature 3: sodium fluoride, pyridinium fluoride / tetrahydrofuran; acetonitrile / 5 h / Ambient temperature 4: MnO2 / CCl4 / 0.5 h 5: 60 percent / NaCN, AgO, MnO2 / 14 h / 40 °C 6: 70 percent / 6 M NaOH / ethanol / 50 °C View Scheme

1: 80 percent / imidazole / dimethylformamide / 18 h / Ambient temperature 2: 90 percent / LiAlH4, TiCl3 / tetrahydrofuran / 0.5 h / Ambient temperature 3: sodium fluoride, pyridinium fluoride / tetrahydrofuran; acetonitrile / 5 h / Ambient temperature 4: MnO2 / CCl4 / 0.5 h View Scheme

Multi-step reaction with 2 steps 1: 80 percent / imidazole / dimethylformamide / 18 h / Ambient temperature2: 90 percent / LiAlH4, TiCl3 / tetrahydrofuran / 0.5 h / Ambient temperature