3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
1: zinc(II) chloride / 150 °C / Inert atmosphere 2: C21H13BF8; hydrogen / deuterated toluene / 17 h / 105 °C / 3040.2 Torr / Inert atmosphere; Cooling with liquid nitrogen View Scheme
参考文献
Eroes, Gabor; Nagy, Krisztina; Mehdi, Hasan; Papai, Imre; Nagy, Peter; Kiraly, Peter; Tarkanyi, Gabor; Soos, Tibor
Chemistry - A European Journal, 2012 , vol. 18, # 2 p. 574 - 585
反应条件
sodium hydroxide in ethanol T=20°C; Claisen-Schmidt condensation;
参考文献
Juvale, Kapil; Pape, Veronika F.S.; Wiese, Michael
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 1 p. 346 - 355
参考文献
Bargellini; Finkelstein
Gazzetta Chimica Italiana, 1912 , vol. 42 II, p. 421
反应条件
bismuth trifluoromethanesulphonate; sodium azide; methanecarbohydroxamic acid in N,N-dimethyl-formamide T=120°C; 24 h;
参考文献
Sridhar, Madabhushi; Mallu, Kishore Kumar Reddy; Jillella, Raveendra; Godala, Kondalreddy; Beeram, Chinaramanaiah; Chinthala, Narsaiah
Synthesis (Germany), 2013 , vol. 45, # 4 art. no. SS-2012-Z0887-OP, p. 507 - 510
反应条件
1: 56 percent / 2 N aq. H2SO4 / 0.5 h / 100 °C 2: 68 percent / Na2CO3 / acetone / 12 h / Heating 3: 55 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 18 h / Heating View Scheme
参考文献
Pogosyan, S. A.; Matevosyan, L. A.; Melik-Ogandzhanyan, A. S.; Safrazbekyan, R. R.; Arzanunts, E. M.; et al.
Pharmaceutical Chemistry Journal, 1986 , vol. 20, # 10 p. 714 - 717
Khimiko-Farmatsevticheskii Zhurnal, 1986 , vol. 20, # 10 p. 1191 - 1195
反应条件
ammonium formate in ethanol 6 h; Reflux;
参考文献
Bea, Han-Seop; Park, Hye-Jeong; Lee, Sang-Hyeup; Yun, Hyungdon
Chemical Communications, 2011 , vol. 47, # 20 p. 5894 - 5896
反应条件
ammonium acetate; malonic acid in ethanol
参考文献
Celgene Corporation
Patent: US5703098 A1, 1997 ;
反应条件
ammonium acetate; malonic acid in ethyl alcohol water
参考文献
THE NUTRASWEET COMPANY, (a Delaware corporation)
Patent: EP355819 A1, 1990 ;
反应条件
ammonium acetate in butan-1-ol Rodionov reaction; Heating;
参考文献
Russian Journal of General Chemistry, , vol. 75, # 7 p. 1113 - 1124
反应条件
1: 1.) t-BuOK / 1.) THF, -78 deg C, 45 min, 2.) THF, -80 deg C 2: 63 percent / H2 / 5percent Pd/C / methanol / 760 Torr / Ambient temperature 3: 85 percent / 6 N HCl / tetrahydrofuran / 3 h / 70 °C View Scheme
参考文献
Cativiela; Diaz-de-Villegas; Galvez
Tetrahedron Asymmetry, 1992 , vol. 3, # 4 p. 567 - 572
