3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
1: carbon tetrabromide With triphenylphosphine in dichloromethane T=0°C; Corey-Fuchs homologation; 0.25 h; 2: 3,4-dimethoxy-benzaldehyde in dichloromethane T=0°C; Corey-Fuchs homologation; 0.55 h; 3: With n-butyllithium in tetrahydrofuran T=-78°C; Corey-Fuchs homologation; 0.666667 h;
参考文献
Fischer, Joshua; Savage, G. Paul; Coster, Mark J.
Organic Letters, 2011 , vol. 13, # 13 p. 3376 - 3379
反应条件
1: 40 percent / acetic anhydride / Heating 2: 59 percent / H2O / acetone 3: H2 / <Rh(R-PROPHOS)(NBD)>PF6 / tetrahydrofuran / 1.5 h View Scheme
参考文献
O'Reilly; Derwin; Lin
Synthesis, 1990 , # 7 p. 550 - 556
反应条件
1: sodium acetate; acetic anhydride / 3.75 h / 40 - 135 °C 2: water; acetone / 6 h / |Reflux 3: [(S)-BINAPRuCl(benzene)]Cl; hydrogen / methanol / 12 h / 20 - 50 °C / 3750.38 Torr / |Autoclave; |Inert atmosphere View Scheme
参考文献
Arava, Veera Reddy; Amasa, Srinivasulu Reddy; Goud Bhatthula, Bharat Kumar; Kompella, Laxmi Srinivas; Matta, Venkata Prasad; Subha
Synthetic Communications, 2013 , vol. 43, # 21 p. 2892 - 2897
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal in methanol T=20°C; P=760.051 Torr; 0.75 h;
参考文献
Xing, Lixin; Wang, Xinyan; Cheng, Chuanjie; Zhu, Rui; Liu, Bo; Hu, Yuefei
Tetrahedron, 2007 , vol. 63, # 38 p. 9382 - 9386
反应条件
water; potassium formiate; palladium on activated charcoal in ethanol T=20°C; 2 h;
参考文献
Baidossi, Mubeen; Joshi, Ashutosh V.; Mukhopadhyay, Sudip; Sasson, Yoel
Synthetic Communications, 2004 , vol. 34, # 4 p. 643 - 650
反应条件
T=85°C; Hydrogenation;
参考文献
Kindler; Gehlhaar
Archiv der Pharmazie (Weinheim, Germany), 1936 , vol. 274, p. 377,385
反应条件
1: Br2 / methanol 2: NaBH4 View Scheme
参考文献
Olivera, Roberto; SanMartin, Raul; Dominguez, Esther; Solans, Xabier; Urtiaga, Miren Karmele; Arriortua, Maria Isabel
Journal of Organic Chemistry, 2000 , vol. 65, # 20 p. 6398 - 6411
反应条件
dihydrogen peroxide; methyltrioxorhenium (VII) in ethanol T=50°C; 24 h;
参考文献
Yamazaki, Shigekazu
Chemistry Letters, 1995 , # 2 p. 127 - 128
反应条件
dihydrogen peroxide; methyltrioxorhenium (VII) T=50°C; 24 h;
参考文献
Yamazaki, Shigekazu
Chemistry Letters, 1995 , # 2 p. 127 - 128
反应条件
1.1: iodine / dichloromethane / 20 °C 2.1: copper(l) iodide / chloroform / 0.17 h / 20 °C 2.2: 1 h 2.3: 12 h / 20 °C View Scheme
参考文献
Fu, Liang; Yao, Chang-Jiang; Chang, Ning-Jie; Chen, Jia-Rong; Lu, Liang-Qiu; Xiao, Wen-Jing
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 3 p. 506 - 508
