3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
1.1: piperidinium acetate / ethanol / 0.5 h 1.2: 77 percent / NaBH3CN / ethanol / 0 - 20 °C 2.1: 74 percent / K2CO3 / dimethylformamide 3.1: 77 percent / TfOH / nitromethane / 0.75 h / 100 °C View Scheme
参考文献
Fillion, Eric; Fishlock, Dan; Wilsily, Ashraf; Goll, Julie M.
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1316 - 1327
反应条件
zeolite Hβ in 1,2-dichloro-ethane 8 h; Heating;
参考文献
Balaji; Chanda, Bhanu M.
Tetrahedron, 1998 , vol. 54, # 43 p. 13237 - 13252
反应条件
1: (i) NaOH, (ii) /BRN= 473899/ 2: HCl / Ambient temperature View Scheme
参考文献
Ogura,K. et al.
Bulletin of the Chemical Society of Japan, 1979 , vol. 52, p. 2013 - 2022
反应条件
1: 99 percent / 50percent aq. NaOH, tetrabutylammonium iodide / CH2Cl2 / 50 °C 2: 61 percent / phenylmethanol / 100 °C 3: 90 percent / NaOAc, PCC/Al2O3 / CH2Cl2 / Heating 4: 95 percent / NaCNBH3, MgSO4 / acetic acid; methanol / Heating 5: 1.) 4N aq. HCl, 2.) H2 / 2.) 10percent Pd/C / 1.) Et2O, MeOH, a) 0 deg C, 30 min, b) RT, overnight, 2.) Et2O, MeOH, RT, 1 atm, 24 h View Scheme
参考文献
Silveira, Claudio C.; Bernardi, Carmem R.; Braga, Antonio L.; Kaufman, Teodoro S.
Tetrahedron Letters, 1999 , vol. 40, # 27 p. 4969 - 4972
反应条件
1: ethanol; aq. NaOH solution 2: aq.-ethanolic hydrochloric acid 3: ethanol; pentyl nitrite; aqueous hydrochloric acid 4: aqueous hydriodic acid; acetic acid anhydride View Scheme
参考文献
Oliverio; Bargellini
Gazzetta Chimica Italiana, 1948 , vol. 78, p. 386,394
反应条件
palladium nanoparticles deposited on porous SBA-15 in cyclohexane T=140°C; 24 h; Molecular sieve;
参考文献
Huang, Yao-Bing; Yang, Zhen; Chen, Meng-Yuan; Dai, Jian-Jun; Guo, Qing-Xiang; Fu, Yao
ChemSusChem, 2013 , vol. 6, # 8 p. 1348 - 1351
反应条件
1: 99 percent / KOH / ethanol / 3 h / 20 °C 2: 90 percent / BBr3 / CH2Cl2 / 0.5 h / 0 °C 3: 65 percent / dimethyl dioxirane / acetone; CH2Cl2 / 1 h / 0 - 20 °C 4: 95 percent / K2CO3 / acetone / 6 h / Heating 5: 71 percent / I2; pyridine / 8 h / Heating 6: 94 percent / BBr3 / CH2Cl2 / 0.5 h / 0 °C 7: 90 percent / dimethyl dioxirane / acetone; CH2Cl2 / 0.33 h / 0 - 20 °C 8: 87 percent / K2CO3 / acetone; CH2Cl2 / 6 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 60, # 11 p. 2647 - 2655
反应条件
1.1: ammonium acetate / acetic acid / 1.5 h / 20 °C / Reflux 2.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / Reflux 3.1: formic acid / 0.17 h / 0 °C 3.2: 24 h / 50 °C View Scheme
参考文献
Shinohara, Tatsumi; Toda, Jun; Sano, Takehiro
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 5 p. 813 - 819
反应条件
1.1: piperidinium acetate / ethanol / 0.5 h 1.2: 77 percent / NaBH3CN / ethanol / 0 - 20 °C 2.1: 76 percent / K2CO3 / dimethylformamide 3.1: 77 percent / Sc(OTf)3 / nitromethane / 0.75 h / 100 °C View Scheme
参考文献
Fillion, Eric; Lou, Tiantong; Liao, E-Ting; Wilsily, Ashraf
Organic Syntheses, 2012 , vol. 89, p. 115 - 125
反应条件
1: piperidine; acetic acid / ethanol / 0.5 h / 20 °C / |Schlenk technique; |Inert atmosphere 2: sodium tris(acetoxy)borohydride / ethanol / 3 h / 20 °C / |Schlenk technique; |Inert atmosphere 3: potassium carbonate / N,N-dimethyl-formamide / 3.5 h / |Schlenk technique; |Inert atmosphere 4: trimethylsilyl trifluoromethanesulfonate / acetonitrile / |Schlenk technique; |Reflux; |Inert atmosphere View Scheme
参考文献
Fillion, Eric; Lou, Tiantong; Liao, E-Ting; Wilsily, Ashraf
Organic Syntheses, 2012 , vol. 89, p. 115 - 125
