3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
sodium disulfite in N,N-dimethyl-formamide 2 h; Reflux;
参考文献
Khan, Khalid Mohammed; Khan, Momin; Ambreen, Nida; Rahim, Fazal; Naureen, Shagufta; Perveen, Shahnaz; Choudhary, M. Iqbal; Voelterc, Wolfgang
Medicinal Chemistry, 2012 , vol. 8, # 3 p. 421 - 427
参考文献
Tani; Ishibashi
Yakugaku Zasshi, 1956 , vol. 76, p. 1064,1067
Chem.Abstr., 1957 , p. 2790
反应条件
(i), (ii) aq. K2CO3, acetone; Multistep reaction;
参考文献
Butterick; Unrau
Canadian Journal of Chemistry, 1974 , vol. 52, # 16 p. 2873 - 2879
反应条件
1: 60 percent / acetic anhydride, NaOAc / acetic acid / 1.) 80 deg C, 10 min, 2.) 143 deg C, 1 h 2: 51 percent / water / acetone / Heating 3: 94 percent / H2 / 5 percent Pd/C / methanol View Scheme
参考文献
Oltz,E.M.; Bruening,R.C.; Smith,M.J.
Journal of the American Chemical Society, 1988 , vol. 110, p. 6162
反应条件
aminosulfonic acid in ethanol T=20°C; 1.5 h;
参考文献
Chaturvedi, Amit K.; Negi, Arvind S.; Khare, Puja
RSC Advances, 2013 , vol. 3, # 14 p. 4500 - 4504
反应条件
sodium acetate in diethylene glycol T=130°C; Wittig reaction; 0.333333 h; SonicationMicrowave irradiation;
参考文献
Rossi; Urbano; Baraglia, A. Carnevale; Serra; Bergamelli; Iannelli; Azzolina; Collina
Synthetic Communications, 2009 , vol. 39, # 18 p. 3254 - 3262
反应条件
potassium hexamethylsilazane T=-78°C;
参考文献
Parker; Fokas
Journal of Organic Chemistry, 1994 , vol. 59, # 14 p. 3927 - 3932
反应条件
1.1: piperidine; pyridine / 105 - 110 °C 1.2: 25 - 30 °C / pH 9 - 10 1.3: 15 - 20 °C / pH 1 - 2 2.1: sulfuric acid / 4 h / 20 °C 2.2: 5 °C View Scheme
参考文献
PIRAMAL LIFE SCIENCES LIMITED; SIVAKUMAR, Meenakshi; JOSHI, Kalpana Sanjay; AWARE, Valmik Sopan; SARDE, Ankush Gangaram; BAGUL, Sandeep Mukunda; MANOHAR, Sonal Mohan
Patent: WO2011/104680 A1, 2011 ;
WO 2011/104680 A1
参考文献
Lewis; Ramage; Robinson
Journal of the Chemical Society, 1935 , p. 1412
反应条件
in toluene T=80°C; 50 h;
参考文献
Bansal, R. K.; Mathur, Suchitra; Jain, Jainendra K.; Sharma, Diwakar
Journal of the Indian Chemical Society, 1988 , vol. 65, p. 134 - 136
