3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
sodium hydroxide in ethanol T=20°C;
参考文献
Cardia, Maria Cristina; Sanna, Maria Luisa; Meleddu, Rita; Distinto, Simona; Yanez, Matilde; Vina, Dolores; Lamela, Manuel; Maccioni, Elias
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # SUPPL.1 p. E87-E92
反应条件
in benzene 50 h; Heating;
参考文献
Bansal, Raj K.; Bhagchandani, Gope
Journal fuer Praktische Chemie (Leipzig), 1981 , vol. 323, # 1 p. 49 - 54
反应条件
Reaktion ueber mehrere Stufen;
参考文献
Haworth; Woodcock
Journal of the Chemical Society, 1946 , p. 999,1001
反应条件
1: 68 percent / acetic anhydride / Heating 2: 84 percent / Na2CO3 3: H2 / <Rh(R-PROPHOS)(NBD)>PF6 / tetrahydrofuran / 17 h 4: 94.8 percent / conc. HCl / H2O / 20 h / Heating 5: conc. HCl / H2O / 1) 3h, 90 deg C, 2) 0 deg C, 16h View Scheme
参考文献
O'Reilly; Derwin; Lin
Synthesis, 1990 , # 7 p. 550 - 556
反应条件
1.1: acetic acid / ethanol / 23 h / Heating 1.2: 74 percent / NaBH4 / ethanol / 0.5 h / 0 - 20 °C 2.1: 100 percent / Ac2O / 1 h / 70 °C 3.1: 84 percent / NaIO4 / H2O; methanol / 5 h / 20 °C 4.1: 56 percent / TFAA / benzene / 4 h / 20 °C 5.1: 80 percent / NiCl*6H2O; NaBH4 / methanol; tetrahydrofuran / 0.33 h / 0 °C 6.1: 98 percent / NaOH / ethanol; H2O / 1 h / Heating View Scheme
参考文献
Horiguchi, Yoshie; Saitoh, Toshiaki; Terakado, Sachiko; Honda, Konomi; Kimura, Tomoko; Toda, Jun; Sano, Takehiro
Heterocycles, 2001 , vol. 54, # 2 p. 967 - 984
反应条件
1: 25 percent / sodium methoxide / methanol / 4 h / -10 °C 2: 88 percent / Rh2(pbf)4 / toluene / 16 h / 40 °C View Scheme
参考文献
Coowar, Djalil; Bouissac, Julien; Hanbali, Mazen; Paschaki, Marie; Mohier, Eliane; Luu, Bang
Journal of Medicinal Chemistry, 2004 , vol. 47, # 25 p. 6270 - 6282
反应条件
sodium 1) MeOH, -19 deg C to 0 deg C, 2) toluene, reflux; Yield given. Multistep reaction;
参考文献
Bunker, Amy M.; Edmunds, Jeremy J.; Berryman, Kent A.; Walker, Donnelle M.; Flynn, Michael A.; Welch, Kathy M.; Doherty, Annette M.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 9 p. 1061 - 1066
反应条件
triethylammonium formate T=95 - 100°C; 72 h;
参考文献
Toth; Kover
Synthetic Communications, 1995 , vol. 25, # 19 p. 3067 - 3074
反应条件
1: 81 percent / pyridine; piperidine / 6 h / 120 °C 2: 100 percent / H2 / Pd/C / ethanol / 0.5 h / 1551.49 Torr View Scheme
参考文献
Sharma, Anuj; Joshi, Bhupendra P.; Sinha, Arun K.
Chemistry Letters, 2003 , vol. 32, # 12 p. 1186 - 1187
反应条件
hydrogenchloride; sodium hydroxide; formic acid; triethylamine in chloroform; water
参考文献
BIOGAL GYOGYSZERGYAR
Patent: EP578850 A1, 1994 ;
