3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
1: With potassium hydroxide; 18-crown-6 ether in dichloromethane T=20°C; Honer-Wadsworth-Emmons reaction; 2: With iodine in n-heptane 12 h; Heating; Further stages.;
参考文献
Kim; Ko; Jae Eun Park; Jung; Sang Kwang Lee; Chun
Journal of Medicinal Chemistry, 2002 , vol. 45, # 1 p. 160 - 164
反应条件
sodium methylate in N,N-dimethyl-formamide T=100°C; Horner-Wadsworth-Emmons reaction; 1.5 h;
参考文献
Murias, Marek; Handler, Norbert; Erker, Thomas; Pleban, Karin; Ecker, Gerhard; Saiko, Philipp; Szekeres, Thomas; Jaeger, Walter
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 21 p. 5571 - 5578
反应条件
piperidine T=160 - 170°C; 20 h; Yields of byproduct given;
参考文献
Prakash, Satya; Khan, Mushtaq A.; Khan, Khaliquz Zaman; Zaman, Asif
Phytochemistry (Elsevier), 1985 , vol. 24, # 3 p. 622 - 624
反应条件
1: 61 percent / decalin / 3 h / Heating 2: 63 percent / NaBH4 / dimethylsulfoxide / 12 h / 70 °C 3: 1.) n-BuLi / 1.) THF, hexane, 0 deg C, 10 min; 2.) THF, r.t., 12 h View Scheme
参考文献
Brown; Brown, Karen M.; Lawrence; Lawrence, Nicholas J.; Liddle; Liddle, John; Muhammad; Muhammad, Faiz; Jackson; Jackson, David A.
Tetrahedron Letters, 1994 , vol. 35, # 36 p. 6733 - 6736
反应条件
tri-n-butyl-tin hydride; silica gel in toluene T=110°C; 6 h;
参考文献
Journal of Organic Chemistry, , vol. 59, # 23 p. 7138 - 7141
反应条件
1: 99 percent / KOH / ethanol / 3 h / 20 °C 2: 90 percent / BBr3 / CH2Cl2 / 0.5 h / 0 °C 3: 97 percent / K2CO3 / acetone / 2 h / Heating View Scheme
参考文献
Chu, Han-Wei; Wu, Huan-Ting; Lee, Yean-Jang
Tetrahedron, 2004 , vol. 60, # 11 p. 2647 - 2655
反应条件
1: 80 percent / KSCN; Triton X-405 / 7 h / 180 °C 2: 12 h / 70 °C View Scheme
参考文献
Bhattacharya, Apurba; Patel, Nitin C.; Vasques, Tomas; Tichkule, Ritesh; Parmar, Gaurang; Wu, Jiejun
Tetrahedron Letters, 2006 , vol. 47, # 4 p. 565 - 567
反应条件
1: 62.7 percent / butylamine / 168 h 2: 47 percent / reduced iron, nickel chloride hexahydrate, concd. hydrochloric acid / toluene; H2O / 4 h / Heating View Scheme
参考文献
Ogura, Katsuyuki; Ohtsuki, Kazuo; Takahashi, Kazumasa; Iida, Hirotada
Chemistry Letters, 1986 , p. 1597 - 1598
反应条件
iron; N-butylamine Yield given. Multistep reaction;
参考文献
Luk'yanov, S. M.
Russian Journal of Organic Chemistry, 1995 , vol. 31, # 7 p. 927 - 933
Zhurnal Organicheskoi Khimii, 1995 , vol. 31, # 7 p. 1002 - 1008
反应条件
Yield given. Multistep reaction;
参考文献
Gladiani, S.; Soccolili, F.
Synthetic Communications, 1982 , vol. 12, # 5 p. 355 - 360
