3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
in tetrahydrofuran; water
参考文献
American Cyanamid Company
Patent: US5677303 A1, 1997 ;
反应条件
sodium hydride in diethylene glycol dimethyl ether 1.) below 20 deg C 2.) below 8 deg C, then 3h, rt then 2 h;
参考文献
Bhatia, M. S.; Rani, Poonam; Xavierkutty, M. C.; Lal, Jawahar
Journal of the Indian Chemical Society, 1987 , vol. 64, # 7 p. 411 - 413
反应条件
piperidine; sulfuric acid 1) pyridine; Yield given. Multistep reaction;
参考文献
Brown; Blakemore; Durant; Emmett; Ganellin; Parsons; Rawlings; Walker
European Journal of Medicinal Chemistry, 1988 , vol. 23, # 1 p. 53 - 62
反应条件
potassium tert-butylate 1.) THF, -20 deg C, 2.) -20 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Osuka, Atsuhiro; Mori, Yasuo; Shimizu, Hirohito; Suzuki, Hitomi
Tetrahedron Letters, 1983 , vol. 24, # 25 p. 2599 - 2602
反应条件
T=100°C; Wittig olefination; 0.166667 h; Title compound not separated from byproducts.;
参考文献
Thiemann, Thies; Watanabe, Masataka; Tanaka, Yasuko; Mataka, Shuntaro
New Journal of Chemistry, 2004 , vol. 28, # 5 p. 578 - 584
反应条件
1: 85 percent / piperidine, pyridine / Heating 2: 59 percent / conc. sulfuric acid / 5 h / Heating View Scheme
参考文献
Potapov, V. M.; Gracheva, R. A.; Sivov, N. A.; Savina, S. A.; Sivova, L. A.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 9 p. 1694 - 1699
Zhurnal Organicheskoi Khimii, 1989 , vol. 25, # 9 p. 1876 - 1881
反应条件
1: NaBH4 / methanol; CH2Cl2 / 1 h 2: PBr3 / diethyl ether / 3 h / Ambient temperature View Scheme
参考文献
Yang, Li-Ming; Lin, Shwu-Jiuan; Yang, Tsang-Hsiung; Lee, Kuo-Hsiung
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 8 p. 941 - 944
反应条件
1: sodium methoxide / methanol / 4 h / -15 °C 2: xylene / 0.25 h / Heating 3: KOH / H2O / 1 h / Heating View Scheme
参考文献
Coowar, Djalil; Bouissac, Julien; Hanbali, Mazen; Paschaki, Marie; Mohier, Eliane; Luu, Bang
Journal of Medicinal Chemistry, 2004 , vol. 47, # 25 p. 6270 - 6282
反应条件
manganese; titanium tetrachloride in tetrahydrofuran T=-10°C; 0.5 h; Inert atmosphere; optical yield given as percent de;
参考文献
Duan, Xin-Fang; Feng, Jian-Xia; Zi, Guo-Fu; Zhang, Zhan-Bin
Synthesis, 2009 , # 2 p. 277 - 282
参考文献
Behal; Tiffeneau
Bulletin de la Societe Chimique de France, 1908 , vol. <4> 3, p. 316
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1905 , vol. 141, p. 597
