3,4-二甲氧基苯甲醛合成路线 （共 996 条）
参考文献
Raiford; Floyd
Journal of Organic Chemistry, 1943 , vol. 8, p. 358,363,365
参考文献
Salway
Journal of the Chemical Society, 1909 , vol. 95, p. 1165
Journal of the Chemical Society, 1911 , vol. 99, p. 267
参考文献
Salway
Journal of the Chemical Society, 1909 , vol. 95, p. 1165
Journal of the Chemical Society, 1911 , vol. 99, p. 267
反应条件
1: 91 percent / bromine / methanol / 1 h / cooling 2: 85 percent / sulfuric acid / 6 h / 90 °C 3: 90 percent / potassium carbonate / acetone / 4 h / Heating View Scheme
参考文献
Chandrasekhar; Reddy, N. Ramakrishna; Rao, Y. Srinivasa
Tetrahedron, 2006 , vol. 62, # 51 p. 12098 - 12107
反应条件
N-bromosuccinmide T=27°C; Solid phase reaction; bromination; 0.0333333 h;
参考文献
Sarma, Jagarlapudi A.R.P.; Nagaraju, Akula; Majumdar, Kanak K.; Samuel, Purnima M.; Das, Indira; Roy, Sujit; McGhie, Alistair J.
Journal of the Chemical Society. Perkin Transactions 2, 2000 , # 6 p. 1119 - 1123
反应条件
1: iodine; silver sulphate / ethanol / 3 h / 20 °C / Inert atmosphere 2: potassium permanganate / acetonitrile; water / 20 °C View Scheme
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C 1.2: 95 percent / tetrahydrofuran; hexane / -78 - 20 °C 2.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C 2.2: 95 percent / tetrahydrofuran; hexane / 3 h / -78 °C 3.1: 85 percent / H2; acetic acid / Pd(OH)2/C / methanol; H2O / 24 h / 20 °C / 760.05 Torr 4.1: 97 percent / trifluoroacetic acid / CH2Cl2 / 15 h / 20 °C View Scheme
参考文献
Davies, Stephen G.; Mulvaney, Andrew W.; Russell, Angela J.; Smith, Andrew D.
Tetrahedron Asymmetry, 2007 , vol. 18, # 13 p. 1554 - 1566
反应条件
1.1: bromine / methanol / 3 h / 20 °C 2.1: nBuLi / hexane; tetrahydrofuran / 0.25 h / 20 °C 2.2: 0.54 g / hexane; tetrahydrofuran / 3 h / 20 °C View Scheme
参考文献
Appukkuttan, Prasad; Dehaen, Wim; Van Der Eycken, Erik
Organic Letters, 2005 , vol. 7, # 13 p. 2723 - 2726
反应条件
1: Na-methylate / dimethylsulfoxide / 0.5 h / 65 - 75 °C 2: HCl cc. / propan-2-ol / 1 h / Heating 3: 96 percent / Na-methylate / ethanol / 24 h / Heating View Scheme
参考文献
Hachtel; Haller; Seydel
Arzneimittel-Forschung/Drug Research, 1988 , vol. 38, # 12 p. 1778 - 1783
反应条件
1: KOtBu 2: POCl3, Et3N 3: NaBH4 View Scheme
参考文献
Barrett,A.G.M. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1979 , p. 652 - 661
