3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
hydrogenchloride; formic acid in N-methyl-acetamide; water
参考文献
BIOGAL GYOGYSZERGYAR
Patent: EP578849 A1, 1994 ;
反应条件
hydrogenchloride; formic acid in water; acetone
参考文献
BIOGAL GYOGYSZERGYAR
Patent: EP578849 A1, 1994 ;
反应条件
1: piperidine; acetic acid / ethanol / 0.5 h / 20 °C / |Schlenk technique; |Inert atmosphere 2: sodium tris(acetoxy)borohydride / ethanol / 3 h / 20 °C / |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Fillion, Eric; Lou, Tiantong; Liao, E-Ting; Wilsily, Ashraf
Organic Syntheses, 2012 , vol. 89, p. 115 - 125
反应条件
1: ethanol 2: NaBH4 3: 73 percent / PPA View Scheme
参考文献
Euerby, Melvin R.; Waigh, Roger D.
Journal of Chemical Research, Miniprint, 1987 , # 2 p. 501 - 526
反应条件
1: NH2OH*HCl; Na2CO3 / ethanol; H2O / 1 h / 60 °C 2: pyridine; NCS / 0.5 h / 60 °C View Scheme
参考文献
Yermolina, Maria V.; Wang, Jizhen; Caffrey, Michael; Rong, Lijun L.; Wardrop, Duncan J.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 3 p. 765 - 781
反应条件
piperidine; benzoic acid in benzene Condensation; refluxing overnight under an argon atmosphere with Dean-Stark trap;
参考文献
Gu, Jian-Xin; Holland, Herbert L.
Synthetic Communications, 1998 , vol. 28, # 18 p. 3305 - 3315
反应条件
1: ethyl bromide With magnesium in diethyl ether 2 h; 2: 3,4-dimethoxy-benzaldehyde in diethyl ether; toluene T=20°C; Grignard reaction;
参考文献
Sharma, Anuj; Joshi, Bhupendra P.; Sinha, Arun K.
Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 12 p. 2231 - 2235
反应条件
1: ethyl bromide With magnesium in diethyl ether 2: 3,4-dimethoxy-benzaldehyde in diethyl ether; toluene T=20°C; 14 h;
参考文献
Tetrahedron, , vol. 62, # 5 p. 847 - 851
参考文献
Roberts, Jeffrey C.; Pincock, James A.
Journal of Organic Chemistry, 2006 , vol. 71, # 4 p. 1480 - 1492
参考文献
Bolton; Hao Ming Wu; Li Qing Hu
Chemical Research in Toxicology, 1996 , vol. 9, # 1 p. 109 - 113
