3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
1: 76 percent / methanol / -10 °C 2: 86 percent / xylene / Heating 3: 85 percent / aq. NaOH / Heating 4: 61 percent / Cu; quinoline / Heating View Scheme
参考文献
Sreenivasa Reddy; Cook, James M.
Tetrahedron Letters, 1994 , vol. 35, # 30 p. 5413 - 5416
反应条件
1: sodium methoxide / methanol / 4 h / -15 °C 2: xylene / 0.25 h / Heating 3: KOH / H2O / 1 h / Heating 4: BBr3; H2O / CH2Cl2 / 4 h / -40 °C View Scheme
参考文献
Molecules, , vol. 11, # 12 p. 968 - 977
反应条件
1: ethanol / 20 °C / |Alkaline conditions 2: iodine / dimethyl sulfoxide / |Reflux View Scheme
参考文献
Juvale, Kapil; Stefan, Katja; Wiese, Michael
European Journal of Medicinal Chemistry, 2013 , vol. 67, p. 115 - 126
反应条件
piperidine; pyridine 0.0833333 h; microwave irradiation;
参考文献
Mitra, Alok Kumar; De, Aparna; Karchaudhuri, Nilay
Synthetic Communications, 1999 , vol. 29, # 4 p. 573 - 581
反应条件
pyridine; acetic acid T=130°C; Knoevenagel-Doebner reaction; 0.133333 h; microwave irradiation;
参考文献
Tetrahedron, , vol. 63, # 4 p. 960 - 965
反应条件
1: water / 2 h / 75 °C 2: FeCl3·6H2O; water / nitromethane / 0.75 h / 110 °C / |Sealed tube View Scheme
参考文献
Garnelis, Thomas; Athanassopoulos, Constantinos M.; Papaioannou, Dionissios; Eggleston, Ian M.; Fairlamb, Alan H.
Chemistry Letters, 2005 , vol. 34, # 2 p. 264 - 265
反应条件
trichlorophosphate T=80 - 90°C; Condensation; Perkin reaction;
参考文献
Simonyan
Pharmaceutical Chemistry Journal, 1999 , vol. 33, # 3 p. 158 - 159
反应条件
ammonium acetate in butan-1-ol Rodionov reaction; Heating;
参考文献
Russian Journal of General Chemistry, , vol. 75, # 7 p. 1113 - 1124
反应条件
sodium methylate; phosphonic acid dimethyl ester 1.) methanol, reflux, 2 h, 2.) 45 min; Yield given. Multistep reaction;
参考文献
Brittelli, David R.
Journal of Organic Chemistry, 1981 , vol. 46, # 12 p. 2514 - 2520
反应条件
1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 °C 2: water; potassium carbonate / methanol / 0.5 h / 20 °C / Inert atmosphere 3: 4-(N,N-dimethlyamino)pyridine / 12 h / 70 °C / Inert atmosphere 4: 1 h / 50 °C / Inert atmosphere; Neat (no solvent); Sealed tube 5: zinc(II) chloride / 1,4-dioxane / 192 h / 100 °C / Inert atmosphere View Scheme
参考文献
Jerezano, Alberto; Jimenez, Fabiola; Del Carmen Cruz, Maria; Montiel, Luisa E.; Delgado, Francisco; Tamariz, Joaquin
Helvetica Chimica Acta, 2011 , vol. 94, # 2 p. 185 - 198
