3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
chloranil; trifluoroacetic acid
参考文献
Hitotsuyanagi, Yukio; Kobayashi, Masatsugu; Fukuyo, Masamoto; Takeya, Koichi; Itokawa, Hideji
Tetrahedron Letters, 1997 , vol. 38, # 48 p. 8295 - 8296
参考文献
Dickinson; Heilbron; Irving
Journal of the Chemical Society, 1927 , p. 1892
反应条件
1: trimethylsilyl cyanide; 3,4-dimethoxy-benzaldehyde With lithium boron tetrafluoride in dichloromethane; acetonitrile T=23°C; 0.5 h; 2: acetic anhydride in dichloromethane; acetonitrile T=23°C; 2.5 h; Further stages.;
参考文献
Yadav; Reddy, B.V. Subba; Vishnumurthy; Chary, Ch. Janardhana
Tetrahedron Letters, 2007 , vol. 48, # 33 p. 5915 - 5918
反应条件
T=20°C; Cooling with iceInert atmosphere;
参考文献
Kumaraswamy; Ankamma
Organic Preparations and Procedures International, 2008 , vol. 40, # 5 p. 447 - 455
反应条件
1: 92 percent / Br2 / methanol 2: 83 percent / conc. H2SO4 4: NaBH4 View Scheme
参考文献
Kueenburg, Bernhard; Czollner, Laszlo; Frohlich, Johannes; Jordis, Ulrich
Organic Process Research and Development, 1999 , vol. 3, # 6 p. 425 - 431
反应条件
1: 91 percent / aq. KOH / ethanol / 16 h / 20 °C 2: 76 percent / H2 / Lindlar catalyst / aq. methanol / 6 h / 2068.59 - 2585.74 Torr 3: 99 percent / K2CO3 / acetone / 20 h / 20 °C 4: 98 percent / (+)-DIP-chloride / tetrahydrofuran / -20 °C View Scheme
参考文献
Keenan, Terence; Yaeger, David R.; Courage, Nancy L.; Rollins, Carl T.; Pavone, Mary Ellen; Rivera, Victor M.; Yang, Wu; Guo, Tao; Amara, Jane F.; Clackson, Tim; Gilman, Michael; Holt, Dennis A.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 8 p. 1309 - 1335
反应条件
1: 70 percent / glacial AcOH / ethanol / 5 h / Heating 2: 1) glacial AcOH, HCl, NaNO2 2) pyridine / 1) water, 0-5 deg C 2) r.t., overnight View Scheme
参考文献
Shrimali; Kalsi; Sah; Barthwal
Journal of the Indian Chemical Society, 1990 , vol. 67, # 9 p. 748 - 752
反应条件
1: With n-butyllithium; N,N,N'-trimethyl-ethylenediamine in hexane; benzene T=0 - 20°C; 2: With phenyllithium in hexane; anhydrous butyl ether; benzene T=0 - 20°C; 9 h; 3: With tetrahydrofuran; 1,2-di-iodoethane in hexane; anhydrous butyl ether; benzene T=-78 - 20°C; 16 h;
参考文献
Nielsen, Daniel K.; Nielsen, Laura L.; Jones, Spencer B.; Toll, Lawrence; Asplund, Matthew C.; Castle, Steven L.
Journal of Organic Chemistry, 2009 , vol. 74, # 3 p. 1187 - 1199
反应条件
iodine; acetic acid; periodic acid; sulfuric acid in water Heating;
参考文献
Hathaway, Bruce A.; White, Kristen L.; McGill, Mark E.
Synthetic Communications, 2007 , vol. 37, # 21 p. 3855 - 3860
反应条件
magnesium sulfate in dichloromethane T=20°C; Inert atmosphere;
参考文献
Ros, Abel; Lopez-Rodriguez, Rocio; Estepa, Beatriz; Alvarez, Eleuterio; Fernandez, Rosario; Lassaletta, Jose M.
Journal of the American Chemical Society, 2012 , vol. 134, # 10 p. 4573 - 4576
