3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
1: 99 percent / BF3*Et2O / CH2Cl2 / 12 h / 0 - 20 °C 2: 26 percent / 2-methyl-2-butene; aq. NaH2PO4; NaClO2 / 2 h / 20 °C View Scheme
参考文献
Gelin, Suzanne; Dolmazon, Rene
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 543 - 546
反应条件
FeIII(TF5PS4P) lt;TF5PS4P = meso-tetrakis(pentafluorophenyl)-β-tetrasulfonatoporphyringt;; tartrate buffer; magnesium monoperoxyphthalate hexahydrate in water; acetonitrile T=0°C; other reagents system; other 1,2-dimethoxyarenes; Mechanism;
参考文献
Artaud, Isabelle; Grennberg, Helena; Mansuy, Daniel
Journal of the Chemical Society, Chemical Communications, 1992 , # 15 p. 1036 - 1038
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 28, # 1-11 p. 37 - 41
反应条件
1: 99 percent / KOH / ethanol / 3 h / 20 °C 2: 90 percent / BBr3 / CH2Cl2 / 0.5 h / 0 °C 3: 97 percent / K2CO3 / acetone / 2 h / Heating 4: 86 percent / dimethyl dioxirane / acetone; CH2Cl2 / 0.5 h / 0 - 20 °C 5: 96 percent / K2CO3 / acetone / 1 h / Heating 6: 99 percent / BBr3 / CH2Cl2 / 0.5 h / 0 °C View Scheme
参考文献
Tetrahedron, , vol. 60, # 11 p. 2647 - 2655
反应条件
ammonium acetate T=90°C; 15 h;
参考文献
ASTRAZENECA AB
Patent: WO2005/61484 A1, 2005 ;
Location in patent: Page/Page column 41 ;
WO 2005/061484 A1
参考文献
Kauffmann
Chemische Berichte, 1917 , vol. 50, p. 635
Chemische Berichte, 1919 , vol. 52, p. 1431
反应条件
1: lithium hydroxide hydrate / tetrahydrofuran / 24 h / |Molecular sieve; |Inert atmosphere; |Reflux 2: palladium 10 on activated carbon; hydrogen / ethanol / 12 h 3: sodium hydroxide / ethanol / 12 h / 20 °C View Scheme
参考文献
Magrioti, Victoria; Nikolaou, Aikaterini; Smyrniotou, Annetta; Shah, Ishita; Constantinou-Kokotou, Violetta; Dennis, Edward A.; Kokotos, George
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 18 p. 5823 - 5829
反应条件
1: 50.7 percent / HCl / ethanol 2: 62.6 percent / NaOH / 16 h View Scheme
参考文献
Al Nakib, Tahsin; Tyndall, D. Vivian; Meegan, Mary Jane
Journal of Chemical Research, Miniprint, 1988 , # 1 p. 301 - 325
反应条件
1: 99 percent / KOH / ethanol / 3 h / 20 °C 2: 90 percent / BBr3 / CH2Cl2 / 0.5 h / 0 °C 3: 65 percent / dimethyl dioxirane / acetone; CH2Cl2 / 1 h / 0 - 20 °C 4: 95 percent / K2CO3 / acetone / 6 h / Heating 5: 71 percent / I2; pyridine / 8 h / Heating 6: 94 percent / BBr3 / CH2Cl2 / 0.5 h / 0 °C 7: 90 percent / dimethyl dioxirane / acetone; CH2Cl2 / 0.33 h / 0 - 20 °C 8: 87 percent / K2CO3 / acetone; CH2Cl2 / 6 h / Heating 9: 80 percent / dimethyl dioxirane / acetone; CH2Cl2 / 0.17 h / 0 - 20 °C 10: 97 percent / K2CO3 / acetone / 1 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 60, # 11 p. 2647 - 2655
反应条件
1: 94 percent / sodium borohydride / methanol / 2 h / 25 °C 2: 95 percent / thionyl chloride / 0 °C 3: 75.5 percent / pyridine / ethanol / 5 h / Heating 4: 95 percent / hydrogen / 5percent palladium on charcoal / ethanol View Scheme
参考文献
Paul, D. Brenton
Australian Journal of Chemistry, 1984 , vol. 37, # 4 p. 893 - 901
