3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
1: ethanol / |Heating
2: sodium tetrahydroborate; acetic acid / benzene / |Reflux
View Scheme
参考文献
Kozlov; Kadutskii; Baranovskii
Russian Journal of Organic Chemistry, 2012 , vol. 48, # 11 p. 1456 - 1463
Zh. Org. Khim., 2012 , vol. 48, # 11 p. 1472 - 1479,8
反应条件
1: in tetrahydrofuran
T=0°C; Green chemistry;
2: With [bis(acetoxy)iodo]benzene
T=0 - 20°C; Green chemistry;
参考文献
Sagara, Prateep Singh; Chebolu, Rajesh; Bahuguna, Ashish; Ravikumar
RSC Advances, 2014 , vol. 4, # 29 p. 15011 - 15013
参考文献
Prescott,B.; Li,C.P.
Journal of Medicinal Chemistry, 1964 , vol. 7, p. 383 - 385
反应条件
in water
1 h; Heating;
参考文献
Tzeng, Cherng-Chyi; Panzica, Raymond P.; Naguib, Fardos N.M.; Kouni, Mahmoud H. el
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 5 p. 1399 - 1404
反应条件
magnesium in tetrahydrofuran
T=20°C; 2 h;
参考文献
Brenna, Elisabetta; Fuganti, Claudio; Grasselli, Piero; Serra, Stefano
European Journal of Organic Chemistry, 2001 , # 7 p. 1349 - 1357
反应条件
in diethyl ether
Addition; 8 h;
参考文献
Zacchino, Susana A.; Lopez, Silvia N.; Pezzenati, German D.; Furlan, Ricardo L.; Santecchia, Carina B.; Munoz, Lorena; Giannini, Fernando A.; Rodriguez, Ana M.; Enriz, Ricardo D.
Journal of Natural Products, 1999 , vol. 62, # 10 p. 1353 - 1357
参考文献
Norcross; Openshaw
Journal of the Chemical Society, 1949 , p. 1174,1178
反应条件
1: aq. NaOH / methanol / 0.5 h / 0 - 5 °C
2: silica gel, NaBH4 / CHCl3; propan-2-ol / 0.25 h / 25 °C
3: 80 percent / dimethylamine hydrochloride, KF / toluene / Heating
4: 76 percent / silica, NaBH4 / propan-2-ol; CHCl3 / 0.25 h / 25 °C
5: 60 percent / aq. chromous chloride / tetrahydrofuran / 0.17 h / Ambient temperature
View Scheme
参考文献
Kodukulla; Trivedi; Vora; Mathur
Synthetic Communications, 1994 , vol. 24, # 6 p. 819 - 832
反应条件
PEG-stabilized Ni nanoparticles in ethylene glycol
T=20°C; Knoevenagel condensation; 0.2 h; chemoselective reaction;
参考文献
Khurana, Jitender M.; Vij, Kanika
Tetrahedron Letters, 2011 , vol. 52, # 28 p. 3666 - 3669
反应条件
1.1: ammonium acetate; acetic acid / 4 h / 90 °C
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 2.5 h / 0 °C / Reflux
2.2: 0 °C
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0.5 h / 20 °C
3.2: 8 h / 20 °C
View Scheme
参考文献
Qian, Wangke; Lu, Weijian; Sun, Haifeng; Li, Zeng; Zhu, Liyuan; Zhao, Rui; Zhang, Lei; Zhou, Shengbin; Zhou, Yu; Jiang, Hualiang; Zhen, Xuechu; Liu, Hong
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 15 p. 4862 - 4871
