3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
1: 85 percent / NH4Ac / toluene
2: 80 percent / NaBH4 / methanol
3: 91 percent / dimethylformamide / Heating
View Scheme
参考文献
LES LABORATOIRES SERVIER; CARRANZA, Maria Del Pilar; GARCIA ARANDA, Maria Isabel; GONZALEZ, José Lorenzo; SANCHEZ, Frédéric
Patent: US2014/107334 A1, 2014 ;
参考文献
Muthukumar; Viswanathamurthi
Journal of Coordination Chemistry, 2010 , vol. 63, # 7 p. 1263 - 1272
反应条件
aluminum oxide
T=20°C; Abramov reaction; 72 h; neat (no solvent);
参考文献
Hudson, Harry R.; Yusuf, Ramon O.; Matthews, Ray W.
Phosphorus, Sulfur and Silicon and the Related Elements, 2008 , vol. 183, # 7 p. 1527 - 1540
反应条件
boron trifluoride diethyl etherate in dichloromethane
T=0 - 20°C; 12 h;
参考文献
Ichige, Takahiro; Miyake, Annu; Kanoh, Naoki; Nakata, Masaya
Synlett, 2004 , # 10 p. 1686 - 1690
反应条件
[Zn(BH4)2(nmi)] in diethyl ether
T=20°C; 0.6 h;
参考文献
Setamdideh, Davood; Khezri, Behrooz
Asian Journal of Chemistry, 2010 , vol. 22, # 7 p. 5766 - 5772
反应条件
1: NaBH4 / methanol
2: pyridine / benzene / Ambient temperature
View Scheme
参考文献
Pincock, J. A.; Wedge, P. J.
Journal of Organic Chemistry, 1994 , vol. 59, # 19 p. 5587 - 5595
反应条件
1: 2) CrO3, H2SO4
2: Al, Hg
3: POCl3 / pyridine
4: 42 percent / toluene / 2 h / Heating
5: 88 percent / bromine / CHCl3 / Ambient temperature
6: 4.1 percent / lithium aluminium hydride / tetrahydrofuran
View Scheme
参考文献
Iwashita, Takashi; Suzuki, Masahiro; Kusumi, Takenori; Kakisawa, Hiroshi
Chemistry Letters, 1980 , p. 383 - 386
反应条件
titanium tetrachloride; zinc in tetrahydrofuran
McMurry Reaction; Inert atmosphereReflux;
参考文献
Hong, Fong-Jiao; Low, Yun-Yee; Chong, Kam-Weng; Thomas, Noel F.; Kam, Toh-Seok
Journal of Organic Chemistry, 2014 , vol. 79, # 10 p. 4528 - 4543
反应条件
1: 1.) Mg / 2.) THF, reflux, overnight
2: 78 percent / H2 / Pd/C
3: 420 mg / BBr3 / CH2Cl2 / 2.5 h / 0 - 20 °C
View Scheme
参考文献
ElSohly, Mahmoud A.; Adawadkar, Prakash D.; Benigni, Daniel A.; Watson, Edna S.; Little, Thomas L.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 5 p. 606 - 611
反应条件
anhydrous diethylamine hydrochloride in toluene
Knoevenagel reaction; 48 h; Heating;
参考文献
Ploypradith, Poonsakdi; Petchmanee, Thaninee; Sahakitpichan, Poolsak; Litvinas, Nichole D.; Ruchirawat, Somsak
Journal of Organic Chemistry, 2006 , vol. 71, # 25 p. 9440 - 9448
