3,4-二甲氧基苯甲醛合成路线 （共 996 条）
参考文献
Groebel,B.-T.; Seebach,D.
Chemische Berichte, 1977 , vol. 110, p. 852 - 866
参考文献
v.Kostanecki; Rudse
Chemische Berichte, 1905 , vol. 38, p. 936
反应条件
1: 89 percent / ammonium acetate / benzene / 6 h / Heating
2: 44 percent / methanol
View Scheme
参考文献
Walker; Boots; Stubbins; Rogers; Davis
Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 174 - 181
反应条件
in ethanol
3 h; Heating;
参考文献
Meisenheimer, John L.; Meisenheimer, John L.; Raya, Diana G.; Stapleton, Michael C.; Goddard, Carl J.
Synthetic Communications, 1989 , vol. 19, # 13-14 p. 2229 - 2236
反应条件
1: 100 percent / H2O / 1 h / Heating
2: 75 percent / sodium borohydride / ethanol / 2 h
View Scheme
参考文献
Tzeng, Cherng-Chyi; Panzica, Raymond P.; Naguib, Fardos N.M.; Kouni, Mahmoud H. el
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 5 p. 1399 - 1404
反应条件
sodium hydroxide in ethanol
T=20°C; 2 h;
参考文献
Lin, Li; Shi, Qian; Nyarko, Alexander K.; Bastow, Kenneth F.; Wu, Chin-Chung; Su, Ching-Yuan; Shih, Charles C.-Y.; Lee, Kuo-Hsiung
Journal of Medicinal Chemistry, 2006 , vol. 49, # 13 p. 3963 - 3972
反应条件
1: 94 percent / piperidine; pyridine / 2 h / 110 °C
2: SOCl2 / benzene / 2 h / 80 °C
3: LiAlH(O-t-Bu)3 / tetrahydrofuran / 2 h / 0 - 5 °C
View Scheme
参考文献
Koul, Surrinder; Koul, Jawahir L.; Taneja, Subhash C.; Dhar, Kanaya L.; Jamwal, Deshvir S.; Singh, Kuldeep; Reen, Rashmeet K.; Singh, Jaswant
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 1 p. 251 - 268
反应条件
sodium hydroxide in water
Yields of byproduct given;
参考文献
Buergi, Christoph; Liu, Gui; Rueedi, Peter
Helvetica Chimica Acta, 1993 , vol. 76, p. 1901 - 1915
参考文献
Meyers,A.I. et al.
Journal of Organic Chemistry, 1973 , vol. 38, p. 36 - 56
反应条件
piperidine in ethanol
参考文献
Ren, Zhongjiao; Cao, Weiguo; Tong, Weiqi; Chen, Jie; Deng, Hongmei; Wu, Danyi
Synthetic Communications, 2008 , vol. 38, # 13 p. 2200 - 2214
