3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
1: 2N NaHSO3 / 3 h / 40 °C
2: H2O / 0.25 h
View Scheme
参考文献
Almsick, Andreas van; Buddrus, Joachim; Hoenicke-Schmidt, Petra; Laumen, Kurt; Schneider, Manfred P.
Journal of the Chemical Society, Chemical Communications, 1989 , # 18 p. 1391 - 1393
反应条件
titanium(III) chloride; potassium carbonate; acetic acid
1) water, 2 h, r.t., 2) t-BuOH, 4 h, 35 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Clerici, Angelo; Porta, Ombretta
Journal of Organic Chemistry, 1993 , vol. 58, # 10 p. 2889 - 2893
参考文献
Moon, Lomary S.; Pal, Mohan; Kasetti, Yoganjaneyulu; Bharatam, Prasad V.; Jolly, Ravinder S.
Journal of Organic Chemistry, 2010 , vol. 75, # 16 p. 5487 - 5498
反应条件
1: 95 percent / NaH / tetrahydrofuran; dimethylsulfoxide / 20 h / Ambient temperature
2: 95 percent / H2 / Pd/C
3: 93 percent / polyphosphoric acid / 4 h / 40 °C
4: 72 percent / NH3(liq.), t-C4H9OK, air / Irradiation
5: 75 percent / 30percent Pd/C / 4 h / 250 °C
View Scheme
参考文献
Beugelmans, Rene; Chastanet, Jacqueline; Ginsburg, Helene; Quintero-Cortes, Leticia; Roussi, Georges
Journal of Organic Chemistry, 1985 , vol. 50, # 24 p. 4933 - 4938
参考文献
Duval; Xuong
Microchimica Acta, 1956 , p. 747
反应条件
acetic anhydride; triethylamine
T=110°C;
参考文献
Schwenk; Papa
Journal of the American Chemical Society, 1945 , vol. 67, p. 1432,1434
反应条件
1: bromination
3: Zn, HCl
View Scheme
参考文献
Estevez; Castedo
Tetrahedron Letters, 1992 , vol. 33, # 45 p. 6883 - 6884
反应条件
in wss. Loesung von pH 10,65;
参考文献
Naik, Mayuri M.; Tilve, Santosh G.; Kamat, Vijayendra P.
Tetrahedron Letters, 2014 , vol. 55, # 22 p. 3340 - 3343
反应条件
1: NaOH / ethanol / 20 °C
2: glacial acetic acid / 72 h / Heating
View Scheme
参考文献
Maki, Yoshifumi; Shimada, Kaoru; Sako, Magoichi; Hirota, Kosaku
Tetrahedron, 1988 , vol. 44, # 11 p. 3187 - 3194
反应条件
1H-imidazole; 18-crown-6 ether; sodium hydride in tetrahydrofuran; benzene
20 h;
参考文献
Katagi, Toyoshi; Shirota, Taeko; Kashiwagi, Masako; Hayashi, Kayo
Heterocycles, 1981 , vol. 15, # 1 p. 493 - 494
