3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
ethanol
anschliesenden Hydrieren an Raney-Nickel;
参考文献
Gardner; Mitchell; Purves
Canadian Journal of Research, Section B: Chemical Sciences, 1948 , vol. 26, p. 668,674, 676
反应条件
ammonium chloride in ethanol
参考文献
Buergi, Christoph; Liu, Gui; Rueedi, Peter
Helvetica Chimica Acta, 1993 , vol. 76, p. 1901 - 1915
反应条件
sodium hydroxide; phosphoric acid in ethanol; benzene
1)reflux 5h 2)reflux 5h;
参考文献
Makin, S. M.; Shavrygina, O. A.; Dobretsova, E. K.; Ermakova, G. A.; Dymshakova, G. M.
Journal of Organic Chemistry USSR (English Translation), 1982 , vol. 18, p. 651 - 656
Zhurnal Organicheskoi Khimii, 1982 , vol. 18, # 4 p. 749 - 755
反应条件
sodium methylate in methanol
-5 deg C, 2 h then 20 deg C, 3 h;
参考文献
Coote, Steven J.; Davies, Stephen G.; Middlemiss, David; Naylor, Alan
Tetrahedron: Asymmetry, 1990 , vol. 1, # 1 p. 33 - 56
反应条件
2: H2SO4
3: m-chloroperbenzoic acid, sodium bicarbonate / CH2Cl2; H2O / 24 h / Heating
View Scheme
参考文献
Moyna, Guillermo; Williams, Howard J.; Scott
Synthetic Communications, 1996 , vol. 26, # 11 p. 2235 - 2239
反应条件
1: 75 percent / LiOCH3 / methanol; dimethylformamide / 24 h / 80 °C
2: 95 percent / H2 / Pd/C / dioxane / 3102.9 Torr
3: 65 percent / aq. HCl 6N / dioxane / 4 h / Heating
4: 90 percent / LiAlH4 / diethyl ether / 3 h / Heating
5: 90 percent / PBr3 / 2 h / 100 °C
View Scheme
参考文献
Bellucci; Teodori; Gualtieri
Farmaco, Edizione Scientifica, 1985 , vol. 40, # 10 p. 730 - 744
反应条件
1.1: 100 percent / 4 Angstroem molecular sieves / toluene / 0 °C
2.1: 95 percent / toluene / 1 h / Heating
3.1: 94 percent / triethylamine / toluene / 1 h / 0 °C
4.1: 95 percent / NaOH / ethanol
5.1: oxalyl chloride / dimethylformamide
5.2: 74 percent / SnCl4
View Scheme
参考文献
Leseche, Bernard; Gilbert, Jacques; Viel, Claude
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 143 - 153
反应条件
1: water; nitric acid / unter Ausschluss von Tageslicht
2: HCl / 50 °C / unter Lichtausschluss
3: zinc-powder; aqueous acetic acid
View Scheme
参考文献
Jin, Jian-Wen; Zhang, Lin; Meng, Guang-Rong; Zhu, Jian-Hua; Zhang, Qian
Synthetic Communications, 2014 , vol. 44, # 3 p. 346 - 351
反应条件
1: 81 percent / piperidine; pyridine / 6 h / 120 °C
2: 100 percent / H2 / Pd/C / ethanol / 1 h / 1551.44 Torr
3: 65.7 percent / NaBH4; TiCl4 / 1,2-dimethoxy-ethane / 18 h / 20 °C
View Scheme
参考文献
Sharma, Mukul; Rajesh, U. Chinna; Rawat, Diwan S.
Journal of the Indian Chemical Society, 2013 , vol. 90, # 10 p. 1853 - 1860
反应条件
1.1: piperidine; pyridine / 4 h / 118 °C
2.1: 56 percent / LAH / tetrahydrofuran / 4 h / 20 °C
3.1: carbonyldiimidazole / tetrahydrofuran / 0.25 h / 45 °C
3.2: 76 percent / 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 24 h / 45 °C
View Scheme
参考文献
Hu, Li Hong; Zou, Hong Bin; Gong, Jing Xu; Li, Hai Bo; Yang, Lei Xiang; Cheng, Wei; Zhou, Chang Xin; Bai, Hua; Gueritte, Francoise; Zhao, Yu
Journal of Natural Products, 2005 , vol. 68, # 3 p. 342 - 348
