3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
Multi-step reaction with 2 steps 1: diethyl ether2: zinc; hydrochloric acid; water
参考文献
Sugimoto Yakugaku Zasshi, 1956 , vol. 76, p. 1045Chem.Abstr., 1957 , p. 3598
反应条件
Multi-step reaction with 2 steps 1: 92 percent / HCl gas / dioxane / 1 h / Heating2: 24 percent / chromium trioxide, 35percent H2SO4 / acetone; H2O / 2 h / Ambient temperature
参考文献
Gatta; Piazza; Del Giudice; Massotti Farmaco, Edizione Scientifica, 1985 , vol. 40, # 12 p. 942 - 955
反应条件
Multi-step reaction with 2 steps 1: 69 percent / HCl gas / CHCl3 / 1 h / 0 °C2: 1.) BuLi / 1.) THF, - 78 deg C, 30 min; 2.) THF, -78 deg C, 90 min; 3.) THF, -78 deg C, 2 h
参考文献
Pelter, Andrew; Ward, Robert S.; Pritchard, Martyn C.; Kay, I. Trevor Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 1603 - 1614
反应条件
Multi-step reaction with 2 steps 1: aq.-ethanolic KOH2: aqueous H2SO4; acetic acid
参考文献
Bellino; Venturella Annali di Chimica (Rome, Italy), 1958 , vol. 48, p. 111,118
反应条件
With biphenyl; sodium in hexane; benzene 10 h; Heating;
参考文献
Pasha, M. A.; Ravindranath, B. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 1068 - 1069
反应条件
Multi-step reaction with 2 steps 1: 50 percent / partially dehydrated barium hydroxide octahydrate / ethanol / 2 h / Heating2: 43 percent / 10 percent H2SO4 / methanol / 7 h / Heating
参考文献
Pouget; Fagnere; Basly; Besson; Champavier; Habrioux; Chulia Pharmaceutical Research, 2002 , vol. 19, # 3 p. 286 - 291
反应条件
Multi-step reaction with 2 steps 1: 56 percent / 2 N aq. H2SO4 / 0.5 h / 100 °C2: 68 percent / Na2CO3 / acetone / 12 h / Heating
参考文献
Pogosyan, S. A.; Matevosyan, L. A.; Melik-Ogandzhanyan, A. S.; Safrazbekyan, R. R.; Arzanunts, E. M.; et al. Pharmaceutical Chemistry Journal, 1986 , vol. 20, # 10 p. 714 - 717Khimiko-Farmatsevticheskii Zhurnal, 1986 , vol. 20, # 10 p. 1191 - 1195
反应条件
Stage #1: With acetamide; acetyl chloride in acetic acid T=0 - 20°C; 4.5 h; Stage #2: With phosphorus trichoride in acetic acid 2 h; Heating; Stage #3: With hydrogenchloride 6 h;
参考文献
Drag, Marcin; Jezierski, Adam; Kafarski, Pawel Chemical communications (Cambridge, England), 2004 , # 9 p. 1132 - 1133
反应条件
Multi-step reaction with 2 steps 1: 68 percent / K2CO3 / propan-2-ol / Heating2: 90 percent / NaBH4 / ethanol / 6 h / Ambient temperature
参考文献
Ogura, Katsuyuki; Ohtsuki, Kazuo; Takahashi, Kazumasa; Iida, Hirotada Chemistry Letters, 1986 , p. 1597 - 1598
反应条件
Multi-step reaction with 3 steps 1: 68 percent / K2CO3 / propan-2-ol / Heating2: 90 percent / NaBH4 / ethanol / 6 h / Ambient temperature3: NaH / dimethylformamide / 1.) 0 deg C, 1 h; 2.) RT, 1 h; 3.) 0 deg C, 6 h; 4.) RT, 18 h
参考文献
Ogura, Katsuyuki; Ohtsuki, Kazuo; Takahashi, Kazumasa; Iida, Hirotada Chemistry Letters, 1986 , p. 1597 - 1598
