3,4-二甲氧基苯乙胺合成路线 （共 365 条）
反应条件
sodium carbonate in diethyl ether T=20°C; 6 h;
参考文献
Vincze, Zoltan; Biro, A. Beatrix; Csekei, Marton; Timari, Geza; Kotschy, Andras
Synthesis, 2006 , # 8 p. 1375 - 1385
反应条件
T=150 - 155°C; 10 h;
参考文献
Ambros; Von Angerer; Wiegrebe
Archiv der Pharmazie, 1988 , vol. 321, # 8 p. 481 - 486
反应条件
2: 60.8 percent / POCl3 / toluene / 1 h / Heating View Scheme
参考文献
Glusa; Gruner; Hagen; Lohmann; Foken
Pharmazie, 1990 , vol. 45, # 6 p. 408 - 410
反应条件
sodium carbonate in dichloromethane; water T=20°C; 2 h;
参考文献
Ploypradith, Poonsakdi; Petchmanee, Thaninee; Sahakitpichan, Poolsak; Litvinas, Nichole D.; Ruchirawat, Somsak
Journal of Organic Chemistry, 2006 , vol. 71, # 25 p. 9440 - 9448
反应条件
dicyclohexyl-carbodiimide in dichloromethane 1.) 0 deg C, 30 min, 2.) 25 deg C, 16 h;
参考文献
McDonald, Edward; Wylie, Robert D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1104 - 1108
反应条件
1: 98 percent / 10percent K2CO3 / diethyl ether; CHCl3 / 0 °C 2: 90 percent / PPE / CHCl3 / Heating 3: acid View Scheme
参考文献
Zheng, Pinguan; Lieberman, Brian P.; Choi, Seok Rye; Ploeessl, Karl; Kung, Hank F.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 11 p. 3435 - 3438
反应条件
in benzene 3 h; Heating;
参考文献
Landais; Robin
Tetrahedron, 1992 , vol. 48, # 35 p. 7185 - 7196
反应条件
potassium phosphate; sodium iodide in sulfolane T=20 - 35°C; Inert atmosphere;
参考文献
Shankar; More, Satish S.; Madhubabu; Vembu; Syam Kumar
Synlett, 2012 , vol. 23, # 7 p. 1013 - 1020
反应条件
1: 79 percent / triethylamine / ethyl acetate / 1 h / 20 °C 2: phosphorus pentoxide / toluene / 0.5 h / Heating View Scheme
参考文献
Stenlake; Waigh; Urwin; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 6 p. 503 - 507
反应条件
1: NaNO2; aqueous acetic acid 2: aqueous HBr / 170 °C View Scheme
参考文献
Schoepf et al.
Justus Liebigs Annalen der Chemie, 1949 , vol. 563, p. 86,89
