3,4-二甲氧基苯乙胺合成路线 （共 365 条）
反应条件
1: 97 percent / aq. K2CO3 / CHCl3 / 1 h / 0 °C
2: PPE / CHCl3 / 3.5 h / Heating
View Scheme
参考文献
Hosoi, Shinzo; Nagao, Motoyoshi; Tsuda, Yoshisuke; Isobe, Kimiaki; Sano, Takehiro; Ohta, Tomihisa
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 10 p. 1505 - 1511
反应条件
triethylamine in dichloromethane
0.75 h; Ambient temperature;
参考文献
Cerecetto, Hugo; Di Maio, Rossanna; Ibarruri, Gerardo; Seoane, Gustavo; Denicola, Ana; Peluffo, Gonzalo; Quijano, Celia; Paulino, Margot
Farmaco, 1998 , vol. 53, # 2 p. 89 - 94
反应条件
in diethyl ether
1 h; Ambient temperature;
参考文献
Hocquaux; Marcot; Redeuilh; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 319 - 329
反应条件
1: 60 percent / triethylamine / diethyl ether / 1 h / Ambient temperature
2: 71 percent / dimethylformamide / 55 h / 100 °C
View Scheme
参考文献
Hocquaux; Marcot; Redeuilh; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 319 - 329
反应条件
in ethanol
6 h; Heating;
参考文献
Amlaiky; Leclerc; Decker; Schwartz
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 5 p. 437 - 439
反应条件
1: 96 percent / Et3N, DMAP / CH2Cl2 / Ambient temperature
2: 92 percent / 2,4-bis(4-methoxyphenyl)-1,3-dithia-2,4-diphosphetane-2,4-disulfide / toluene / 2 h / Heating
View Scheme
参考文献
Lete, Esther; Collado, M. Isabel; Sotomayor, Nuria; Vicente, Teresa; Villa, Maria-Jesus
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 6 p. 1751 - 1758
反应条件
1: in toluene
3 h; Heating;
2: With trifluoroacetic acid in toluene
48 h; Heating;
参考文献
Padwa, Albert; Lee, Hyoung Ik; Rashatasakhon, Paitoon; Rose, Mickea
Journal of Organic Chemistry, 2004 , vol. 69, # 24 p. 8209 - 8218
反应条件
1: toluene / 3 h / Heating
2: 1.7 g / trifluoroacetic acid / toluene / 48 h / Heating
View Scheme
参考文献
Cassayre, Jerome; Quiclet-Sire, Beatrice; Saunier, Jean-Baptiste; Zard, Samir Z.
Tetrahedron Letters, 1998 , vol. 39, # 49 p. 8995 - 8998
反应条件
T=20°C; Schotten-Baumann Reaction; 6 h;
参考文献
Nunes, Geandra B.L.; Policarpo, Paola R.; Costa, Luciana M.; Silva, Teresinha G. Da; Militao, Gardenia Carmen G.; Camara, Celso A.; Filho, Jose Maria Barbosa; Gutierrez, Stanley Juan C.; Islam, Mohammed T.; De Freitas, Rivelilson M.
Molecules, 2014 , vol. 19, # 4 p. 4595 - 4607
反应条件
1: 59 percent / triethylamine / CHCl3 / 20 °C
2: 96 percent / Et3N / methanol / 24 h / 20 °C
View Scheme
参考文献
Zhu, Xiaoxiang; Yu, Qian-sheng; Greig, Nigel H.; Flippen-Anderson, Judith L.; Brossi, Arnold
Heterocycles, 2003 , vol. 59, # 1 p. 115 - 128
