3,4-二甲氧基苯乙胺合成路线 （共 365 条）
反应条件
dicyclohexyl-carbodiimide in tetrahydrofuran
参考文献
Gilbert,J. et al.
Farmaco, Edizione Scientifica, 1978 , vol. 33, p. 237 - 252
反应条件
trifluoroacetic acid
5 h; Heating;
参考文献
Coskun, Necdet; Tuncman, Selen
Tetrahedron, 2006 , vol. 62, # 7 p. 1345 - 1350
反应条件
1: toluene / 3 h / Heating
2: TFA / 90 h / Heating
View Scheme
参考文献
Wendlandt, Alison E.; Stahl, Shannon S.
Journal of the American Chemical Society, 2014 , vol. 136, # 1 p. 506 - 512
反应条件
in 1,4-dioxane
T=120°C; 12 h;
参考文献
El-Subbagh, Hussein; Wittig, Thomas; Decker, Michael; Elz, Sigurd; Nieger, Martin; Lehmann, Jochen
Archiv der Pharmazie, 2002 , vol. 335, # 9 p. 443 - 448
参考文献
Wiesner et al.
Journal of the American Chemical Society, 1955 , vol. 77, p. 675,682
反应条件
pyridine in dichloromethane
T=20°C; 12 h;
参考文献
Welch, Karen T.; Virga, Kristopher G.; Whittemore, Neil A.; Oezen, Can; Wright, Edward; Brown, Cynthia L.; Lee, Richard E.; Serpersu, Engin H.
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 22 p. 6252 - 6263
反应条件
dacarbazine in N,N-dimethyl-formamide
参考文献
Chen, Xiaofang; Wang, Li; Du, Yu; Wu, Yanbin; Jia, Xiaojian; Yang, Yuan; Hong, Bin
Molecules, 2011 , vol. 16, # 11 p. 9178 - 9193
参考文献
Child; Pyman
Journal of the Chemical Society, 1931 , p. 36,47
参考文献
Zellner,H.; Zellner,G.
Helvetica Chimica Acta, 1966 , vol. 49, p. 913 - 939
反应条件
1: 100 percent / iPr2NEt / dimethylsulfoxide / 16 h / 70 °C
2: H2 / 20 percent Pd(OH)2/C / methanol / 24 h / 760 Torr
View Scheme
参考文献
Zellner,H.; Zellner,G.
Helvetica Chimica Acta, 1966 , vol. 49, p. 913 - 939
