N,N-二乙基-4-氨基苯甲醛合成路线 （共 64 条）
反应条件
acetic acid
Knoevenagel condensation; 0.5 h; Grinding;
参考文献
Sharif, Ahsan; Ahmed, Ejaz; Munawar, Munawar Ali; Jabeen, Shamsa; Khan, Misbah-Ul-Ain; Begum, Robina; Farrukh, Aleeza; Ashraf, Muhammad; Arshad, Shafia; Afza, Nighat
Journal of the Chemical Society of Pakistan, 2011 , vol. 33, # 4 p. 578 - 586
参考文献
Winkelmann,E. et al.
Arzneimittel Forschung, 1976 , vol. 26, p. 1543 - 1547
参考文献
Matsuoka, M.; Takao, M.; Kitao, T.; Fujiwara, T.; Nakatsu, K.
Molecular Crystals and Liquid Crystals (1969-1991), 1990 , vol. 182, p. 71 - 79
反应条件
sodium hydroxide; sulfuric acid; urea; N,N-diethylaniline in hydrogenchloride; water; toluene
参考文献
Ciba-Geigy Corporation
Patent: US4533499 A1, 1985 ;
反应条件
1: 2 h / 100 °C
2: sodium tetrahydroborate / methanol / 12 h
View Scheme
参考文献
Ouyang, Qin; Tong, Qin; Feng, Rentian; Myint, Kyaw-Zeyar; Yang, Peng; Xie, Xiang-Qun
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 4 p. 387 - 392
参考文献
Matsuoka, M.; Takao, M.; Kitao, T.; Fujiwara, T.; Nakatsu, K.
Molecular Crystals and Liquid Crystals (1969-1991), 1990 , vol. 182, p. 71 - 79
反应条件
piperidine; toluene
T=120 - 125°C;
参考文献
Ramsey et al.
Journal of the American Chemical Society, 1947 , vol. 69, p. 67
参考文献
Tipson
Journal of the American Chemical Society, 1945 , vol. 67, p. 507,508, 510
反应条件
sodium methylate; benzene
参考文献
Zimmer; Rothe
Journal of Organic Chemistry, 1959 , vol. 24, p. 28,30
反应条件
zinc(II) chloride
T=180°C;
参考文献
Clapp; Tipson
Journal of the American Chemical Society, 1946 , vol. 68, p. 1332
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Bahner et al.
Journal of Organic Chemistry, 1958 , vol. 23, p. 1060
