N-哌嗪甲酸乙酯合成路线

参考文献

SPOFA, spojene podniky pro zdravotnickou vyrobu
Patent: US4243805 A1, 1981 ;

120-43-4N-哌嗪甲酸乙酯+

332-42-34-氟溴乙基苯

70931-36-1

参考文献

Bartl; Dlabac; Protiva
Collection of Czechoslovak Chemical Communications, 1980 , vol. 45, # 11 p. 3182 - 3189

120-43-4N-哌嗪甲酸乙酯

21867-64-11-丙基哌嗪+

71172-70-8乙基4-丙基哌嗪-1-羧酸酯

参考文献

G. D. Searle and Co.
Patent: US5461047 A1, 1995 ;

120-43-4N-哌嗪甲酸乙酯

71172-70-8乙基4-丙基哌嗪-1-羧酸酯

参考文献

Kanamitsu, Norimasa; Osaki, Takashi; Itsuji, Yutaka; Yoshimura, Masakazu; Tsujimoto, Hisashi; Soga, Manabu
Chemical and Pharmaceutical Bulletin, 2007 , vol. 55, # 12 p. 1682 - 1688

120-43-4N-哌嗪甲酸乙酯+

627-18-93-溴-1-丙醇

7483-27-44-(3-羟基丙基)-1-哌嗪羧酸乙酯

参考文献

Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China; LI, Song; WANG, Hongliang; XIAO, Junhai; ZHANG, Xian; WANG, Lili; ZHENG, Zhibing; ZHONG, Wu; XIE, Yunde; LI, Xingzhou; ZHOU, Xinbo; ZHAO, Guoming; WANG, Xiaokui
Patent: EP2602252 A1, 2013 ;
Location in patent: Paragraph 0045 ;

120-43-4N-哌嗪甲酸乙酯+

16013-85-72,6-二氯-3-硝基吡啶

75167-21-4

参考文献

Radl, Stanislav; Hradil, Pavel
Collection of Czechoslovak Chemical Communications, 1991 , vol. 56, # 11.1 p. 2420 - 2429

120-43-4N-哌嗪甲酸乙酯

16013-85-72,6-二氯-3-硝基吡啶+

92741-37-2+

75167-21-4+

92741-38-3

参考文献

Matsumoto; Miyamoto; Minamida; et al.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 3 p. 673 - 679

120-43-4N-哌嗪甲酸乙酯

682341-20-4

参考文献

Kermack; Tebrich
Journal of the Chemical Society, 1940 , p. 202,204

120-43-4N-哌嗪甲酸乙酯+

87587-21-1

87587-19-72-[1-[2-[(4-乙氧羰基哌嗪-1-基)(硫代)甲基]肼基]乙基]吡啶1-氧化物

参考文献

Scovill, John P.; Klayman, Daniel L.; Lambros, Chris; Childs, George E.; Notsch, John D.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 1 p. 87 - 91

120-43-4N-哌嗪甲酸乙酯+

6482-24-22-溴乙基甲基醚

88708-34-3

参考文献

Polivka; Ryska; Holubek; et al.
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 8 p. 2395 - 2410