5-氨基-1-(2,6-二氯-对三氟甲基苯胺基)-3-腈-4-三氟甲基硫基吡唑合成路线 （共 19 条）
反应条件
1.1: nitrosyl-sulphuric acid; acetic acid / 30 - 55 °C 1.2: 0 - 15 °C 2.1: dichloromethane View Scheme
反应条件
1.1: sulfuryl dichloride; 1-methyl-pyrrolidin-2-one / 1-methyl-pyrrolidin-2-one; chlorobenzene / 8 h / 55 - 60 °C 2.1: nitrosyl-sulphuric acid; acetic acid / 30 - 55 °C 2.2: 0 - 15 °C 3.1: dichloromethane View Scheme
反应条件
1: With dichloro-acetic acid; sulfuric acid T=15°C; 0.5 h; 2: With dihydrogen peroxide in water T=15°C; Product distribution / selectivity;
参考文献
IRVITA PLANT PROTECTION, A BRANCH OF CELSIUS PROPERTY B.V; LEVIN, Anat; GRABARNICK, Michael
Patent: WO2012/7938 A1, 2012 ;
Location in patent: Page/Page column 9-10 ;
反应条件
hydrogenchloride; sodium tungstate in water; 1,2-dichloro-ethane T=2 - 8°C; Large scale;
参考文献
ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED; BRISTOW, James Timothy
Patent: WO2013/37291 A1, 2013 ;
Location in patent: Page/Page column 17; 18; 19 ;
反应条件
dihydrogen peroxide; trifluoroacetic acid in dichloromethane T=10 - 12°C; 3 h;
参考文献
Tang, Ri-Yuan; Zhong, Ping; Lin, Qiu-Lian
Journal of Fluorine Chemistry, 2006 , vol. 127, # 7 p. 948 - 953
反应条件
dihydrogen peroxide; boric acid; trifluoroacetic acid in chlorobenzene
参考文献
Bayer Cropscience SA
Patent: US6620943 B1, 2003 ;
反应条件
dihydrogen peroxide; trifluoroacetic acid in dichloromethane T=10 - 12°C; 3 h;
参考文献
Tang, Ri-Yuan; Zhong, Ping; Lin, Qiu-Lian
Journal of Fluorine Chemistry, 2006 , vol. 127, # 7 p. 948 - 953
反应条件
3-chloro-benzenecarboperoxoic acid in chloroform; water
参考文献
RHONE-POULENC AGRICULTURE LIMITED
Patent: EP295117 A1, 1988 ;
反应条件
potassium permanganate; magnesium sulfate in water; acetone T=20°C;
参考文献
Hainzl, Dominik; Cole, Loretta M.; Casida, John E.
Chemical Research in Toxicology, 1998 , vol. 11, # 12 p. 1529 - 1535
