5-三氟甲基-2,3-吡啶二羧酸二乙酯合成路线 （共 2 条）
反应条件
sodium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride T=120°C; P=11251.1 Torr; 18 h;
参考文献
Roche Palo Alto LLC
Patent: US2009/143589 A1, 2009 ;
Location in patent: Page/Page column 4-5 ;
US 20090143589 A1
反应条件
bis-triphenylphosphine-palladium(II) chloride; sodium acetate; 1,4-di(diphenylphosphino)-butane T=120°C; P=11400.8 Torr; 2 h; Autoclave;
参考文献
Crettaz, Roger; Waser, Jerome; Bessard, Yves
Organic Process Research and Development, 2001 , vol. 5, # 6 p. 572 - 574
