1-甲基-4-硝基-2-(三氟乙酰)-1H-咪唑合成路线 （共 9 条）
反应条件
sulfuric acid; nitric acid; acetic anhydride T=0 - 20°C; 24 h;
参考文献
Jaramillo, David; Liu, Qi; Aldrich-Wright, Janice; Tor, Yitzhak
Journal of Organic Chemistry, 2004 , vol. 69, # 23 p. 8151 - 8153
反应条件
sulfuric acid; nitric acid in acetic anhydride Ambient temperature;
参考文献
Nishiwaki, Eiji; Tanaka, Shigeaki; Lee, Hideaki; Shibuya, Masayuki
Heterocycles, 1988 , vol. 27, # 8 p. 1945 - 1952
参考文献
Wurtz, Nicholas R.; Turner, James M.; Baird, Eldon E.; Dervan, Peter B.
Organic Letters, 2001 , vol. 3, # 8 p. 1201 - 1203
反应条件
sodium hydride 0.5 h; Ambient temperature;
参考文献
Nishiwaki, Eiji; Tanaka, Shigeaki; Lee, Hideaki; Shibuya, Masayuki
Heterocycles, 1988 , vol. 27, # 8 p. 1945 - 1952
反应条件
1: 70 percent / methanol / 3 h 2: 91 percent / hydrogen / Pd/C / methanol / 31 h 3: 87 percent / potassium tert-butoxide; H2O / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Wurtz, Nicholas R.; Turner, James M.; Baird, Eldon E.; Dervan, Peter B.
Organic Letters, 2001 , vol. 3, # 8 p. 1201 - 1203
反应条件
1: 0.5 h / Heating 2: H2 / 10percent Pd/C / methanol; dimethylformamide / 2 h / Ambient temperature View Scheme
参考文献
Huang, Liren; Lown, J. William
Heterocycles, 1995 , vol. 41, # 6 p. 1181 - 1196
反应条件
1: T=40°C; 0.166667 h; 2: With sodium hydride 2 h;
参考文献
UNIVERSITY OF SASKATCHEWAN
Patent: WO2007/45096 A1, 2007 ;
Location in patent: Page/Page column 45; 86 ;
参考文献
Jaramillo, David; Liu, Qi; Aldrich-Wright, Janice; Tor, Yitzhak
Journal of Organic Chemistry, 2004 , vol. 69, # 23 p. 8151 - 8153
反应条件
1: 70 percent / methanol / 3 h
2: 91 percent / hydrogen / Pd/C / methanol / 31 h
View Scheme
参考文献
Jaramillo, David; Liu, Qi; Aldrich-Wright, Janice; Tor, Yitzhak
Journal of Organic Chemistry, 2004 , vol. 69, # 23 p. 8151 - 8153
