1201594-21-9合成路线 （共 10 条）
反应条件
1: iodine; silver trifluoromethanesulfonate / chloroform / 65 °C 2: manganese; trifluoroacetic acid / NiBr2bipy / N,N-dimethyl-formamide / 50 °C 3: water; sulfuric acid / 1,4-dioxane View Scheme
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Patent: US2011/77406 A1, 2011 ;
反应条件
1: iodine; silver trifluoromethanesulfonate / chloroform / 65 °C 2: manganese; trifluoroacetic acid / NiBr2bipy / N,N-dimethyl-formamide / 50 °C 3: potassium phosphate / Ni(PCy3)2Cl2 / toluene / 130 °C View Scheme
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Patent: US2011/77406 A1, 2011 ;
反应条件
1.1: [Ni0(1,5-cyclooctadiene)2]; sodium t-butanolate; 1,3-bis(2,6-diisopropylphenyl)imidazolinium chloride / 1,4-dioxane / 3 h / 80 °C / Inert atmosphere 2.1: N-iodo-succinimide; trifluoroacetic acid / 14 h / 23 °C / Inert atmosphere 2.2: 23 °C 3.1: trans-1,2-cyclohexanediamine; potassium carbonate; copper(l) chloride / 1,4-dioxane / 15 h / 110 °C / Inert atmosphere; Darkness 4.1: 7 h / 23 °C 4.2: 23 °C View Scheme
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; GARG, Neil K.; RAMGREN, Stephen D.; SILBERSTEIN, Amanda L.; QUASDORF, Kyle W.
Patent: WO2012/94622 A2, 2012 ;
反应条件
1.1: [Ni0(1,5-cyclooctadiene)2]; sodium t-butanolate; 1,3-bis(2,6-diisopropylphenyl)imidazolinium chloride / 1,4-dioxane / 3 h / 80 °C / Inert atmosphere 2.1: N-iodo-succinimide; trifluoroacetic acid / 14 h / 23 °C / Inert atmosphere 2.2: 23 °C 3.1: trans-1,2-cyclohexanediamine; potassium carbonate; copper(l) chloride / 1,4-dioxane / 15 h / 110 °C / Inert atmosphere; Darkness View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 9 p. 2171 - 2173
反应条件
Multi-step reaction with 3 steps 1: iodine; silver trifluoromethanesulfonate / chloroform / 65 °C2: manganese; trifluoroacetic acid / NiBr2bipy / N,N-dimethyl-formamide / 50 °C3: potassium phosphate / Ni(PCy3)2Cl2 / toluene / 130 °C
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA Patent: US2011/77406 A1, 2011 ;
反应条件
Stage #1: With silver trifluoromethanesulfonate; sodium hydroxide in methanol T=0°C; 0.5 h; Inert atmosphere; Stage #2: With Selectfluor in tetrahydrofuran T=23°C; 16 h; Molecular sieve;
参考文献
Quasdorf, Kyle W.; Riener, Michelle; Petrova, Krastina V.; Garg, Neil K. Journal of the American Chemical Society, 2009 , vol. 131, # 49 p. 17748 - 17749
反应条件
Multi-step reaction with 2 steps 1: Inert atmosphere2: Inert atmosphere
参考文献
Ramgren, Stephen D.; Silberstein, Amanda L.; Yang, Yang; Garg, Neil K. Angewandte Chemie - International Edition, 2011 , vol. 50, # 9 p. 2171 - 2173
反应条件
With iodine; silver trifluoromethanesulfonate in chloroform T=65°C; Show Experimental Procedure
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA Patent: US2011/77406 A1, 2011 ; Location in patent: Page/Page column 9-10; sheet 14/14 ;
反应条件
Multi-step reaction with 2 steps 1: iodine; silver trifluoromethanesulfonate / chloroform / 65 °C2: manganese; trifluoroacetic acid / NiBr2bipy / N,N-dimethyl-formamide / 50 °C
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA Patent: US2011/77406 A1, 2011 ;
反应条件
Multi-step reaction with 2 steps 1.1: [Ni0(1,5-cyclooctadiene)2]; sodium t-butanolate; 1,3-bis(2,6-diisopropylphenyl)imidazolinium chloride / 1,4-dioxane / 3 h / 80 °C / Inert atmosphere2.1: N-iodo-succinimide; trifluoroacetic acid / 14 h / 23 °C / Inert atmosphere2.2: 23 °C
参考文献
Ramgren, Stephen D.; Silberstein, Amanda L.; Yang, Yang; Garg, Neil K. Angewandte Chemie - International Edition, 2011 , vol. 50, # 9 p. 2171 - 2173
