2,6-二氟-4-甲基苯甲醛合成路线 （共 2 条）
反应条件
1: 1,3-difluoro-5-methylbenzene With n-butyllithium in diethyl ether; hexane T=-50°C; 1.83333 h; 2: N,N-dimethyl-formamide in diethyl ether; hexane T=-50°C; 1.83333 h; 3: With sulfuric acid; water in diethyl ether; hexane
参考文献
MERCK SHARP andamp;; DOHME CORP.; KOYAMA, Hiroo; SAHOO, Soumya, P.; YANG, Ginger Xu-Qiang; MILLER, Daniel, J.
Patent: WO2010/129208 A1, 2010 ;
Location in patent: Page/Page column 32 ;
WO 2010/129208 A1
反应条件
1: With sodium hydroxide; silver(l) oxide in hexane; water 1.5 h; 2: With hydrogenchloride in hexane; water pH=2;
参考文献
MERCK SHARP andamp;; DOHME CORP.; KOYAMA, Hiroo; SAHOO, Soumya, P.; YANG, Ginger Xu-Qiang; MILLER, Daniel, J.
Patent: WO2010/129208 A1, 2010 ;
Location in patent: Page/Page column 32-33 ;
WO 2010/129208 A1
