3-(1-吡咯烷)-5-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-吡啶合成路线 （共 2 条）
反应条件
potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in N,N-dimethyl-formamide T=120°C; Inert atmosphere;
参考文献
GLAXO WELLCOME MANUFACTURING PTE LTD.; CHEN, Deborah; LEE, Kiew, Ching; TERRELL, Lamont, Roscoe
Patent: WO2011/75559 A1, 2011 ;
Location in patent: Page/Page column 61 ;
反应条件
1: sodium t-butanolate / 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; tris-(dibenzylideneacetone)dipalladium(0) / toluene / 2 h / 100 °C / Inert atmosphere 2: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct / N,N-dimethyl-formamide / 120 °C / Inert atmosphere View Scheme
参考文献
GLAXO WELLCOME MANUFACTURING PTE LTD.; CHEN, Deborah; LEE, Kiew, Ching; TERRELL, Lamont, Roscoe
Patent: WO2011/75559 A1, 2011 ;
