6-氯-3-甲基-2-吡啶甲腈合成路线 （共 4 条）
反应条件
1: With trichlorophosphate 6 h; Reflux; 2: With water
参考文献
MERCK and CO., INC.
Patent: WO2009/155156 A1, 2009 ;
Location in patent: Page/Page column 62-63 ;
WO 2009/155156 A1
反应条件
1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 °C 2: trichlorophosphate / 6 h / Reflux View Scheme
参考文献
MERCK and CO., INC.
Patent: WO2009/155156 A1, 2009 ;
WO 2009/155156 A1
反应条件
1.1: potassium hydroxide; water / Reflux 1.2: 20 °C 2.1: methanol / tetrahydrofuran / 2 h / 20 °C View Scheme
参考文献
MERCK and CO., INC.
Patent: WO2009/155156 A1, 2009 ;
WO 2009/155156 A1
反应条件
1: With water; potassium hydroxide Reflux; 2: With hydrogenchloride in water T=20°C;
参考文献
MERCK and CO., INC.
Patent: WO2009/155156 A1, 2009 ;
Location in patent: Page/Page column 63 ;
WO 2009/155156 A1
