[S-(E)]-3-[[[(2-羧基乙基)硫代][3-[2-(7-氯-2-喹啉基)乙烯基]苯基]甲基]硫代]丙酸1-甲酯合成路线 (共 6 条)
反应条件
water; Triton X-100 T=40°C; lipase, phosphate buffer, pH = 7.5; Kinetics;
参考文献
Hughes; Bergan; Amato; Reider; Grabowski
Journal of Organic Chemistry, 1989 , vol. 54, # 8 p. 1787 - 1788
反应条件
in water T=37°C; 336 h; Pseudomonas sp. lipase, Triton X-100, Na2HPO4, H3PO4, pH 7.5; Yield given;
参考文献
Shinkai, I; Bhupathy, M
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 1 p. 127 - 130
参考文献
Hughes; Bergan; Amato; Reider; Grabowski
Journal of Organic Chemistry, 1989 , vol. 54, # 8 p. 1787 - 1788
反应条件
in toluene T=100°C; 6 h;
参考文献
Shinkai, I; Bhupathy, M
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 1 p. 127 - 130
反应条件
in dichloromethane; toluene 1.) <5 deg C to 20 deg C, 5 h, 2.) 40 deg C, 15 h; Yield given;
参考文献
Hughes, D. L.; Bergan, J. J.; Amato, J. S.; Bhupathy, M.; Leazer, J. L.; et al.
Journal of Organic Chemistry, 1990 , vol. 55, # 26 p. 6252 - 6259
参考文献
Sidler, Daniel R.; Lovelace, Thomas C.; McNamara, James M.; Reider, Paul J.
Journal of Organic Chemistry, 1994 , vol. 59, # 6 p. 1231 - 1233