3-羟基-2-喹喔啉羧酸合成路线 (共 13 条)
反应条件
sulfuric acid; potassium nitrate in water T=0 - 20°C;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2005/56547 A2, 2005 ;
Location in patent: Page/Page column 48-49 ;
WO 2005/056547 A2
反应条件
dihydrogen peroxide; acetic acid
参考文献
Newbold; Spring
Journal of the Chemical Society, 1948 , p. 519,521
反应条件
1: H2O2; acetic acid
2: dimethyl sulfate; aqueous NaOH
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参考文献
Newbold; Spring
Journal of the Chemical Society, 1948 , p. 519,521