7-氯-咪唑并[1,2-a]吡啶-2-羧酸乙酯合成路线 （共 5 条）
反应条件
sodium carbonate in water pH=8;
参考文献
JANSSEN RandD IRELAND; COOYMANS, Ludwig Paul; HU, Lili; JONCKERS, Tim Hugo Maria; RABOISSON, Pierre Jean-Marie Bernard; TAHRI, Abdellah; VAN HOOF, Steven Maurice Paula; VENDEVILLE, Sandrine Marie Helene
Patent: WO2012/80451 A1, 2012 ;
Location in patent: Page/Page column 25 ;
反应条件
in ethylene glycol dimethyl ether; ethanol T=20°C; 4 h; Reflux;
参考文献
FENG, Yangbo; CHEN, Yen Ting; SESSIONS, Hampton; MISHRA, Jitendra K.; CHOWDHURY, Sarwat; YIN, Yan; LOGRASSO, Philip; LUO, Jun-Li; BANNISTER, Thomas; SCHROETER, Thomas
Patent: WO2011/50245 A1, 2011 ;
Location in patent: Page/Page column 108 ;
WO 2011/050245 A1
反应条件
1: ethylene glycol dimethyl ether / 1 h / 20 °C 2: ethanol / 3 h / Reflux 3: sodium carbonate / water / pH 8 View Scheme
反应条件
1: ethylene glycol dimethyl ether / 1 h / 20 °C 2: ethanol / 3 h / Reflux 3: sodium carbonate / water / pH 8 View Scheme
反应条件
1: With water; lithium hydroxide hydrate in tetrahydrofuran T=20°C; 3 h; 2: With hydrogenchloride in tetrahydrofuran; water
参考文献
FENG, Yangbo; CHEN, Yen Ting; SESSIONS, Hampton; MISHRA, Jitendra K.; CHOWDHURY, Sarwat; YIN, Yan; LOGRASSO, Philip; LUO, Jun-Li; BANNISTER, Thomas; SCHROETER, Thomas
Patent: WO2011/50245 A1, 2011 ;
Location in patent: Page/Page column 109 ;
WO 2011/050245 A1
