N-[2-[[(2,3-二氟苯基)甲基]硫代]-6-[[(1r,2r)-2,3-二羟基-1-甲基丙基]氨基]-4-嘧啶]-1-氮杂丁烷磺酰胺合成路线 （共 2 条）
反应条件
caesium carbonate; bis(dibenzylideneacetone)-palladium(0); 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in 1,4-dioxane T=105°C; 1.5 h; Inert atmosphere; Product distribution / selectivity;
参考文献
MEGHANI, PREMJI; ROBBINS, ANDREW JAMES; STONEHOUSE, JEFFREY PAUL
Patent: US2010/16275 A1, 2010 ;
Location in patent: Page/Page column 12 ;
反应条件
toluene-4-sulfonic acid in methanol; water T=60°C; 20 h; Product distribution / selectivity;
参考文献
MEGHANI, PREMJI; ROBBINS, ANDREW JAMES; STONEHOUSE, JEFFREY PAUL
Patent: US2010/16275 A1, 2010 ;
Location in patent: Page/Page column 14 ;
