1: With lithium aluminium tetrahydride in tetrahydrofuran
T=50°C; CoolingInert atmosphere;
2: With water in tetrahydrofuran
Ice water added into reaction;
参考文献
DARA BIOSCIENCES, INC.; MIDDLEMISS, David; INGOLD, Kenneth, J.
Patent: WO2010/8473 A1, 2010 ;
Location in patent: Page/Page column 20; 21 ;
